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Defy Medical vs Lemonaid Health: Which Is Better?

Head-to-head comparison of Defy Medical and Lemonaid Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 66.1/100), leading on trust & safety, experience, reputation. Lemonaid Health comes out ahead on value, product range. Lemonaid Health has the lower entry price (from $10/mo vs $150/mo), so the better value depends on which treatment you need.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
66

A long-running, broad-scope telehealth generalist now operating under new nonprofit ownership following 23andMe's 2025 bankruptcy.

Visit Lemonaid Health

Score Breakdown

DimensionDefy MedicalLemonaid Health
Overall Score71.9/100 ✓66.1/100
Trust & Safety30%72/100 ✓62/100
Value25%60/10068/100 ✓
Experience20%78/100 ✓65/100
Product Range15%78/10080/100 ✓
Reputation10%80/100 ✓55/100

At a Glance

Founded20112013
HeadquartersTampa, FLSan Francisco, CA
Publicly tradedNoNo
Treatment categories34
Treatments listed45
Starting price$150/mo$10/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalLemonaid Health
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$129–$399
GLP-1 Weight Loss Program
Sexual Health—$25–$90
ED Treatment (Sildenafil/Tadalafil)

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Lemonaid Health

+Broad national telehealth generalist spanning sexual health, weight loss, hair loss, mental health, women's health and primary care under one account.
+Low-friction ED pricing: a single $25 consult covers up to 12 refills, with generic medication priced from $2/pill.
+More than a decade of operating history (founded 2013) with an established patient base and four regional medical groups providing licensed physician coverage.
−Ownership in flux: 23andMe acquired Lemonaid for roughly $400M in 2021, then filed for bankruptcy in 2025 and sold it to nonprofit TTAM Research Institute for approximately $10M — patients have no visibility into whether care continuity, medical staffing, or data handling changed under the new owner.
−Full pricing for most services beyond the advertised ED and GLP-1 offers is not published and only appears after intake.
−Trustpilot reviews cite inconsistent provider conduct, including reports of rude or dismissive clinicians and at least one unexplained prescription refusal for a long-term patient.
Read the full Lemonaid Health review →

Defy Medical vs Lemonaid Health — FAQ

Is Defy Medical better than Lemonaid Health?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 66.1/100), leading on trust & safety, experience, reputation. Lemonaid Health comes out ahead on value, product range. Lemonaid Health has the lower entry price (from $10/mo vs $150/mo), so the better value depends on which treatment you need.

Is Defy Medical or Lemonaid Health cheaper?

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Lemonaid Health has the lower starting price (from $10/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Lemonaid Health both offer?

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Both platforms treat Weight Loss / GLP-1, Sexual Health. Defy Medical covers 3 treatment categories total and Lemonaid Health covers 4.

Still deciding?

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