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Defy Medical vs MadeMed: Which Is Better?

Head-to-head comparison of Defy Medical and MadeMed based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 57.3/100), leading on trust & safety, experience, product range, reputation. MadeMed comes out ahead on value. MadeMed has the lower entry price (from $30/mo vs $150/mo), so the better value depends on which treatment you need.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
57

MadeMed is a Houston-registered telehealth brand selling compounded injectable and oral GLP-1s, sermorelin, NAD+ and tadalafil through the Xpedicare provider network.

Visit MadeMed

Score Breakdown

DimensionDefy MedicalMadeMed
Overall Score71.9/100 ✓57.3/100
Trust & Safety30%72/100 ✓55/100
Value25%60/10066/100 ✓
Experience20%78/100 ✓45/100
Product Range15%78/100 ✓72/100
Reputation10%80/100 ✓45/100

At a Glance

Founded2011—
HeadquartersTampa, FLHouston, TX
Publicly tradedNoNo
Treatment categories33
Treatments listed47
Starting price$150/mo$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalMadeMed
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$99–$199
Compounded Semaglutide (injectable)
Sexual Health—$30–$90
Tadalafil

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

MadeMed

+Offers both injectable and oral/sublingual versions of semaglutide, tirzepatide and sermorelin, plus NAD+ as injection or nasal spray
+Operating entity, provider network (Xpedicare) and a partner pharmacy (Red Rock) are named in the terms and About page
+Advertised GLP-1 entry pricing from $99/mo is at the low end of the market
−Product pages showed no pricing or product detail during our research, in a direct fetch or a real browser
−Advertised prices and state coverage (about 40 states) come from brand-issued press releases and can't be verified on-site
−No Trustpilot or other independent patient reviews; public coverage is mostly paid newswire content
Read the full MadeMed review →

Defy Medical vs MadeMed — FAQ

Is Defy Medical better than MadeMed?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 57.3/100), leading on trust & safety, experience, product range, reputation. MadeMed comes out ahead on value. MadeMed has the lower entry price (from $30/mo vs $150/mo), so the better value depends on which treatment you need.

Is Defy Medical or MadeMed cheaper?

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MadeMed has the lower starting price (from $30/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and MadeMed both offer?

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Both platforms treat Weight Loss / GLP-1, Sexual Health. Defy Medical covers 3 treatment categories total and MadeMed covers 3.

Still deciding?

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