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Defy Medical vs Pallas Health: Which Is Better?

Head-to-head comparison of Defy Medical and Pallas Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 65.7/100), leading on trust & safety, experience, reputation. Pallas Health comes out ahead on value, product range. Pallas Health has the lower entry price (from $60/mo vs $150/mo), so the better value depends on which treatment you need.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
66

Pallas Health is a July 2026-launched telehealth platform offering compounded and branded GLP-1s, longevity peptides, women's HRT, ED and prescription skincare, with unusually detailed compliance disclosures.

Visit Pallas Health

Score Breakdown

DimensionDefy MedicalPallas Health
Overall Score71.9/100 ✓65.7/100
Trust & Safety30%72/100 ✓66/100
Value25%60/10070/100 ✓
Experience20%78/100 ✓58/100
Product Range15%78/10080/100 ✓
Reputation10%80/100 ✓48/100

At a Glance

Founded20112026
HeadquartersTampa, FLNewark, DE
Publicly tradedNoNo
Treatment categories36
Treatments listed412
Starting price$150/mo$60/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalPallas Health
Hormone Therapy$150–$250
Women's Bioidentical HRT
$66–$90
Women's HRT (estradiol topical/cream/patch, estriol cream)
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$159–$239
Compounded Semaglutide (injectable)
Sexual Health—$60–$199
ED Treatment (sildenafil/tadalafil + pycnogenol, vardenafil, Trimix)

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Pallas Health

+Detailed clinical-disclosure page names the operating entity, provider network (Lion MD), dispensing pharmacies and state-by-state visit rules
+Prices published for every product, including branded options (Wegovy pill, Foundayo, pens at cash rates)
+Broad catalog for a new entrant: compounded and branded GLP-1s, NAD+, sermorelin, glutathione, women's HRT, ED and prescription skincare
−Launched July 2026 with no public patient reviews, so service quality is unproven
−Billed every 4 weeks (13 charges a year); the $239 semaglutide renewal is well above the $139 first month
−A real-time video visit is required in 7 states plus DC, which adds friction for those patients
Read the full Pallas Health review →

Defy Medical vs Pallas Health — FAQ

Is Defy Medical better than Pallas Health?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 65.7/100), leading on trust & safety, experience, reputation. Pallas Health comes out ahead on value, product range. Pallas Health has the lower entry price (from $60/mo vs $150/mo), so the better value depends on which treatment you need.

Is Defy Medical or Pallas Health cheaper?

▾

Pallas Health has the lower starting price (from $60/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Pallas Health both offer?

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Both platforms treat Hormone Therapy, Weight Loss / GLP-1, Sexual Health. Defy Medical covers 3 treatment categories total and Pallas Health covers 6.

Still deciding?

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