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Defy Medical vs Shameless Care: Which Is Better?

Head-to-head comparison of Defy Medical and Shameless Care based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 66/100), leading on trust & safety, experience, product range, reputation. Shameless Care comes out ahead on value. Shameless Care has the lower entry price (from $63/mo vs $150/mo), so the better value depends on which treatment you need.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
66

Shameless Care is an Illinois sexual-health telehealth company selling ED and female-arousal medications, comprehensive STI testing, DoxyPEP and UTI/BV/yeast treatment as one-time purchases.

Visit Shameless Care

Score Breakdown

DimensionDefy MedicalShameless Care
Overall Score71.9/100 ✓66/100
Trust & Safety30%72/100 ✓68/100
Value25%60/10068/100 ✓
Experience20%78/100 ✓66/100
Product Range15%78/100 ✓66/100
Reputation10%80/100 ✓55/100

At a Glance

Founded20112022
HeadquartersTampa, FLSt. Charles, IL
Publicly tradedNoNo
Treatment categories34
Treatments listed410
Starting price$150/mo$63/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalShameless Care
Sexual Health—$99–$199
DoxyPEP

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Shameless Care

+One-time purchases with no auto-renewal, which avoids the recurring-charge complaints common in the category
+Every price is posted on the site, all-in with consult, prescription and shipping (e.g. UTI treatment $63, Shameless Duo from $130)
+Covers men's and women's sexual health, including STI testing, DoxyPEP, herpes suppression and female arousal treatments, which most ED-focused brands don't
−Two of its three named partner pharmacies (Curexa, Belmar) received FDA compounding warning letters in 2023
−Review evidence is mostly the brand's own on-site testimonials; little independent Trustpilot or Reddit footprint
−Compounded ED troches cost about $7–11 per dose, well above generic sildenafil or tadalafil tablets
Read the full Shameless Care review →

Defy Medical vs Shameless Care — FAQ

Is Defy Medical better than Shameless Care?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 66/100), leading on trust & safety, experience, product range, reputation. Shameless Care comes out ahead on value. Shameless Care has the lower entry price (from $63/mo vs $150/mo), so the better value depends on which treatment you need.

Is Defy Medical or Shameless Care cheaper?

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Shameless Care has the lower starting price (from $63/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Shameless Care both offer?

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Both platforms treat Sexual Health. Defy Medical covers 3 treatment categories total and Shameless Care covers 4.

Still deciding?

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