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Defy Medical vs TelyRx: Which Is Better?

Head-to-head comparison of Defy Medical and TelyRx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

TelyRx scores higher overall in our independent evaluation (72.3/100 vs 71.9/100), leading on value, product range. Defy Medical comes out ahead on trust & safety, experience, reputation.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
72
TelyRx
Good

TelyRx is a publicly listed online pharmacy platform where patients choose from 500+ generic and branded medications and pay a one-time $22 provider-review fee for an asynchronous prescription from an independent, state-licensed clinician.

Visit TelyRx

Score Breakdown

DimensionDefy MedicalTelyRx
Overall Score71.9/10072.3/100 ✓
Trust & Safety30%72/100 ✓70/100
Value25%60/10072/100 ✓
Experience20%78/100 ✓74/100
Product Range15%78/10080/100 ✓
Reputation10%80/100 ✓65/100

At a Glance

Founded2011—
HeadquartersTampa, FLClearwater, FL
Publicly tradedNoYes (TSX: TELY)
Treatment categories37
Treatments listed49
Starting price$150/mo$22.99/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalTelyRx
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$699.99–$1199.99
Branded Zepbound
Sexual Health—$27.99
Generic Sildenafil

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

TelyRx

+Every catalog price is visible before signup; the only clinical fee is a one-time $22 provider review
+Owns its licensed retail pharmacies, so fulfilment and pharmacist support stay in-house
+Very broad catalog (500+ medications) that includes chronic-condition generics such as lisinopril, albuterol and metformin, plus birth control, ED and hair loss
−Branded GLP-1s are priced near list (Wegovy from $1,399.99), well above manufacturer self-pay programs
−Prescribing is questionnaire-only and done by independent providers, with no ongoing clinical relationship
−Recurring complaints about shipping delays and refills charged without the patient's authorization
Read the full TelyRx review →

Defy Medical vs TelyRx — FAQ

Is Defy Medical better than TelyRx?

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TelyRx scores higher overall in our independent evaluation (72.3/100 vs 71.9/100), leading on value, product range. Defy Medical comes out ahead on trust & safety, experience, reputation.

Is Defy Medical or TelyRx cheaper?

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TelyRx has the lower starting price (from $22.99/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and TelyRx both offer?

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Both platforms treat Weight Loss / GLP-1, Sexual Health. Defy Medical covers 3 treatment categories total and TelyRx covers 7.

Still deciding?

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