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Defy Medical vs Wellorithm: Which Is Better?

Head-to-head comparison of Defy Medical and Wellorithm based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 54.8/100), leading on trust & safety, experience, product range, reputation. Wellorithm comes out ahead on value.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
55
Wellorithm
Below Average

Wellorithm is a Miami-based GLP-1 platform that sells compounded semaglutide ($147 first month, then $247 per 28 days) and tirzepatide ($249, then $349), and also lists branded GLP-1s, NAD+, sermorelin and tadalafil.

Visit Wellorithm

Score Breakdown

DimensionDefy MedicalWellorithm
Overall Score71.9/100 ✓54.8/100
Trust & Safety30%72/100 ✓45/100
Value25%60/10068/100 ✓
Experience20%78/100 ✓55/100
Product Range15%78/100 ✓65/100
Reputation10%80/100 ✓35/100

At a Glance

Founded20112025
HeadquartersTampa, FLMiami, FL
Publicly tradedNoNo
Treatment categories34
Treatments listed42
Starting price$150/mo$247/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalWellorithm
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$247
Compounded Semaglutide (injectable)
Sexual Health——

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Wellorithm

+First-month pricing is competitive: compounded semaglutide $147 and tirzepatide $249, with no membership fee and free shipping
+Written weight-loss guarantee: refund of up to four months of fees if a new patient loses less than 10% after 16 adherent weeks (terms apply)
+Broad catalog spanning compounded injectables and tablets, branded GLP-1s, NAD+, sermorelin and tadalafil
−Ongoing prices rise $100 after month one ($247 / $349), and 28-day billing means 13 charges a year
−Medical group and dispensing pharmacy are not named, and the About page shows placeholder 'specialist' profiles with no credentials
−The site advertises a 4.5 Trustpilot score that doesn't match its thin actual Trustpilot profile, which includes a report of an unauthorized $899 charge and a delayed refund
Read the full Wellorithm review →

Defy Medical vs Wellorithm — FAQ

Is Defy Medical better than Wellorithm?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 54.8/100), leading on trust & safety, experience, product range, reputation. Wellorithm comes out ahead on value.

Is Defy Medical or Wellorithm cheaper?

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Defy Medical has the lower starting price (from $150/mo vs $247/mo for Wellorithm). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Wellorithm both offer?

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Both platforms treat Weight Loss / GLP-1, Sexual Health. Defy Medical covers 3 treatment categories total and Wellorithm covers 4.

Still deciding?

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