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Defy Medical vs Winona: Which Is Better?

Head-to-head comparison of Defy Medical and Winona based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Winona scores higher overall in our independent evaluation (74.5/100 vs 71.9/100), leading on value, experience. Defy Medical comes out ahead on trust & safety, product range.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
75
Winona
Good

Women-focused telehealth delivering personalized bioidentical hormone replacement therapy for menopause, with in-house compounding pharmacies across 33 states.

Visit Winona

Score Breakdown

DimensionDefy MedicalWinona
Overall Score71.9/10074.5/100 ✓
Trust & Safety30%72/100 ✓70/100
Value25%60/10075/100 ✓
Experience20%78/10085/100 ✓
Product Range15%78/100 ✓65/100
Reputation10%80/10080/100

At a Glance

Founded20112020
HeadquartersTampa, FLAustin, TX
Publicly tradedNoNo
Treatment categories35
Treatments listed411
Starting price$150/mo$9/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalWinona
Hormone Therapy$150–$250
Women's Bioidentical HRT
$9
DHEA Capsules
Sexual Health—$79
Sildenafil Arousal Cream

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Winona

+Vertically integrated: in-house compounding pharmacies, proprietary EHR, employed physicians
+Strong patient satisfaction: 4.6/5 Trustpilot with 6,000+ reviews, 80% report symptom relief in 3 months
+Accessible pricing: $54-$149/mo for core HRT with free consultations and shipping
−No insurance billing — entirely out-of-pocket (though HSA/FSA accepted)
−No blood work or lab testing required before or during treatment — a clinical concern
−Limited to 33 US states and Puerto Rico — unavailable in 17 states
Read the full Winona review →

Defy Medical vs Winona — FAQ

Is Defy Medical better than Winona?

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Winona scores higher overall in our independent evaluation (74.5/100 vs 71.9/100), leading on value, experience. Defy Medical comes out ahead on trust & safety, product range.

Is Defy Medical or Winona cheaper?

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Winona has the lower starting price (from $9/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Winona both offer?

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Both platforms treat Hormone Therapy, Sexual Health. Defy Medical covers 3 treatment categories total and Winona covers 5.

Still deciding?

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