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DudeMeds vs Niagen Plus: Which Is Better?

Head-to-head comparison of DudeMeds and Niagen Plus based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 59.7/100), leading on trust & safety, experience, reputation. DudeMeds comes out ahead on product range. DudeMeds has the lower entry price (from $39/mo vs $149/mo), so the better value depends on which treatment you need.

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DudeMeds is a Florida-based men's telehealth platform built around low-cost all-inclusive TRT that has expanded into GLP-1s, ED, hair loss, NAD+ and women's HRT.

Visit DudeMeds
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Prescription-only telehealth program from Nasdaq-listed Niagen Bioscience (formerly ChromaDex) selling an at-home injection kit of nicotinamide riboside (NR), an NAD+ precursor, rather than NAD+ itself.

Visit Niagen Plus

Score Breakdown

DimensionDudeMedsNiagen Plus
Overall Score59.7/10064.7/100 ✓
Trust & Safety30%55/10078/100 ✓
Value25%70/10070/100
Experience20%45/10058/100 ✓
Product Range15%78/100 ✓36/100
Reputation10%50/10068/100 ✓

At a Glance

Founded20212024
HeadquartersFloridaLos Angeles, CA
Publicly tradedNoYes (NAGE)
Treatment categories71
Treatments listed51
Starting price$39/mo$149/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDudeMedsNiagen Plus
Longevity & Peptides—$149
Niagen At-Home Injection Kit (NR chloride 500 mg, ~28 days)

DudeMeds

+All-inclusive TRT from $77/month bundles testosterone, estrogen blocker, supplies, labs and televisits, among the lowest headline TRT prices in telehealth
+Broad catalog under one account: TRT and enclomiphene, compounded and branded GLP-1s, ED, hair loss, NAD+ and LDN
+No separate membership or doctor fee on GLP-1 plans, with free shipping (per third-party pricing checks)
−Trustpilot 2.3/5 (11 reviews) with reports of unauthorized multi-month renewal charges and no company replies to negative reviews
−Patients report the member portal has been non-functional for months, plus refill delays and lost lab work
−GLP-1 pricing not published; third-party audit found the advertised $149/month entry price unavailable at checkout
Read the full DudeMeds review →

Niagen Plus

+Backed by a public company with 25+ years of NAD+-precursor research; it holds the patent on the active ingredient (Niagen NRCl)
+Compounded by a 503B outsourcing facility (FDA-registered, cGMP) rather than a patient-specific 503A lab alone
+Flat, published $149 kit price includes the provider consult, a ~28-day supply, supplies and free Next Day Air shipping
−Only one product, and it is NR (an NAD+ precursor), not NAD+; the studies comparing it with NAD+ IV are small and company-sponsored
−The kit showed 'more stock coming soon' at the time of research, so availability is not reliable
−The site does not name the telehealth medical group or the dispensing 503A pharmacy
Read the full Niagen Plus review →

DudeMeds vs Niagen Plus — FAQ

Is DudeMeds better than Niagen Plus?

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Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 59.7/100), leading on trust & safety, experience, reputation. DudeMeds comes out ahead on product range. DudeMeds has the lower entry price (from $39/mo vs $149/mo), so the better value depends on which treatment you need.

Is DudeMeds or Niagen Plus cheaper?

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DudeMeds has the lower starting price (from $39/mo vs $149/mo for Niagen Plus). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do DudeMeds and Niagen Plus both offer?

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Both platforms treat Longevity & Peptides. DudeMeds covers 7 treatment categories total and Niagen Plus covers 1.

Still deciding?

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