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Effecty vs Enhance.MD: Which Is Better?

Head-to-head comparison of Effecty and Enhance.MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 66.8/100), leading on trust & safety, reputation. Effecty comes out ahead on value, experience, product range. Effecty has the lower entry price (from $55/mo vs $169/mo), so the better value depends on which treatment you need.

67

New York-based cash-pay telehealth brand selling compounded GLP-1s, longevity injectables (NAD+, sermorelin, glutathione) and estradiol HRT with no membership fee and published tiered pricing.

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67

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

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Score Breakdown

DimensionEffectyEnhance.MD
Overall Score66.8/10066.9/100 ✓
Trust & Safety30%60/10076/100 ✓
Value25%76/100 ✓60/100
Experience20%72/100 ✓68/100
Product Range15%66/100 ✓60/100
Reputation10%55/10065/100 ✓

At a Glance

Founded20242019
HeadquartersNew York, NYSan Diego, CA
Publicly tradedNoNo
Treatment categories42
Treatments listed95
Starting price$55/mo$169/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEffectyEnhance.MD
Weight Loss / GLP-1$80
Metformin
$169
Microdose Tirzepatide
Longevity & Peptides$95–$150
Lipotropic (MIC) + B12
$169
NAD+ Therapy

Effecty

+No membership fee, and prices are published per product and don't change with dose (semaglutide $130–$170/mo, tirzepatide $190–$235/mo)
+Card is held, not charged, until a prescription is written; shipping is free and expedited
+4.6/5 on Trustpilot across ~1,300 reviews, most citing fast support responses
−Only operating since November 2024; BBB rating is B with three closed complaints
−Visits are chat-only, and the compounding pharmacies are not named on the site
−Lowest advertised prices require 12-month prepayment; month-to-month runs 25–30% higher
Read the full Effecty review →

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

Effecty vs Enhance.MD — FAQ

Is Effecty better than Enhance.MD?

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Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 66.8/100), leading on trust & safety, reputation. Effecty comes out ahead on value, experience, product range. Effecty has the lower entry price (from $55/mo vs $169/mo), so the better value depends on which treatment you need.

Is Effecty or Enhance.MD cheaper?

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Effecty has the lower starting price (from $55/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Effecty and Enhance.MD both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. Effecty covers 4 treatment categories total and Enhance.MD covers 2.

Still deciding?

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