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Effecty vs Josie: Which Is Better?

Head-to-head comparison of Effecty and Josie based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Effecty scores higher overall in our independent evaluation (66.8/100 vs 57.6/100), leading on trust & safety, value, experience, product range, reputation.

67

New York-based cash-pay telehealth brand selling compounded GLP-1s, longevity injectables (NAD+, sermorelin, glutathione) and estradiol HRT with no membership fee and published tiered pricing.

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58
Josie
Fair

Small menopause-focused telehealth brand selling compounded and branded GLP-1s, microdose GLP-1 maintenance plans and estradiol/progesterone HRT at flat published prices.

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Score Breakdown

DimensionEffectyJosie
Overall Score66.8/100 ✓57.6/100
Trust & Safety30%60/100 ✓50/100
Value25%76/100 ✓70/100
Experience20%72/100 ✓58/100
Product Range15%66/100 ✓60/100
Reputation10%55/100 ✓45/100

At a Glance

Founded2024—
HeadquartersNew York, NY—
Publicly tradedNoNo
Treatment categories43
Treatments listed97
Starting price$55/mo$90/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEffectyJosie
Weight Loss / GLP-1$80
Metformin
$189
Microdose GLP-1 Maintenance (semaglutide or tirzepatide)
Hormone Therapy$55–$180
Estradiol (tablet, cream or patch) + Progesterone
$90–$100
Estradiol Patch or Cream (HRT)
Women's Health——

Effecty

+No membership fee, and prices are published per product and don't change with dose (semaglutide $130–$170/mo, tirzepatide $190–$235/mo)
+Card is held, not charged, until a prescription is written; shipping is free and expedited
+4.6/5 on Trustpilot across ~1,300 reviews, most citing fast support responses
−Only operating since November 2024; BBB rating is B with three closed complaints
−Visits are chat-only, and the compounding pharmacies are not named on the site
−Lowest advertised prices require 12-month prepayment; month-to-month runs 25–30% higher
Read the full Effecty review →

Josie

+Flat pricing at any dose, published before intake: compounded semaglutide $249/mo ($194/mo prepaid annually), tirzepatide $349/mo ($233/mo annually)
+Offers injectable, oral ODT and microdose ($189/mo) GLP-1 formats alongside HRT in one women's-midlife intake
+Names its lead clinician (Dr. Ana Lisa Carr, MD, board-certified in family medicine) and says it serves all 50 states
−FDA warning letter (Feb 20, 2026) for misbranded compounded semaglutide/tirzepatide marketing
−White-label setup: Josie is a trade name of One Eleven Nutrition LLC on the CareValidate platform, and its terms say it doesn't control provider decisions
−An $80 consultation fee applies if a provider approves a plan and the patient declines medication, and filled orders are non-refundable
Read the full Josie review →

Effecty vs Josie — FAQ

Is Effecty better than Josie?

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Effecty scores higher overall in our independent evaluation (66.8/100 vs 57.6/100), leading on trust & safety, value, experience, product range, reputation.

Is Effecty or Josie cheaper?

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Effecty has the lower starting price (from $55/mo vs $90/mo for Josie). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Effecty and Josie both offer?

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Both platforms treat Weight Loss / GLP-1, Hormone Therapy, Women's Health. Effecty covers 4 treatment categories total and Josie covers 3.

Still deciding?

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