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Effecty vs Niagen Plus: Which Is Better?

Head-to-head comparison of Effecty and Niagen Plus based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Effecty scores higher overall in our independent evaluation (66.8/100 vs 64.7/100), leading on value, experience, product range. Niagen Plus comes out ahead on trust & safety, reputation.

67

New York-based cash-pay telehealth brand selling compounded GLP-1s, longevity injectables (NAD+, sermorelin, glutathione) and estradiol HRT with no membership fee and published tiered pricing.

Visit Effecty
65

Prescription-only telehealth program from Nasdaq-listed Niagen Bioscience (formerly ChromaDex) selling an at-home injection kit of nicotinamide riboside (NR), an NAD+ precursor, rather than NAD+ itself.

Visit Niagen Plus

Score Breakdown

DimensionEffectyNiagen Plus
Overall Score66.8/100 ✓64.7/100
Trust & Safety30%60/10078/100 ✓
Value25%76/100 ✓70/100
Experience20%72/100 ✓58/100
Product Range15%66/100 ✓36/100
Reputation10%55/10068/100 ✓

At a Glance

Founded20242024
HeadquartersNew York, NYLos Angeles, CA
Publicly tradedNoYes (NAGE)
Treatment categories41
Treatments listed91
Starting price$55/mo$149/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEffectyNiagen Plus
Longevity & Peptides$95–$150
Lipotropic (MIC) + B12
$149
Niagen At-Home Injection Kit (NR chloride 500 mg, ~28 days)

Effecty

+No membership fee, and prices are published per product and don't change with dose (semaglutide $130–$170/mo, tirzepatide $190–$235/mo)
+Card is held, not charged, until a prescription is written; shipping is free and expedited
+4.6/5 on Trustpilot across ~1,300 reviews, most citing fast support responses
−Only operating since November 2024; BBB rating is B with three closed complaints
−Visits are chat-only, and the compounding pharmacies are not named on the site
−Lowest advertised prices require 12-month prepayment; month-to-month runs 25–30% higher
Read the full Effecty review →

Niagen Plus

+Backed by a public company with 25+ years of NAD+-precursor research; it holds the patent on the active ingredient (Niagen NRCl)
+Compounded by a 503B outsourcing facility (FDA-registered, cGMP) rather than a patient-specific 503A lab alone
+Flat, published $149 kit price includes the provider consult, a ~28-day supply, supplies and free Next Day Air shipping
−Only one product, and it is NR (an NAD+ precursor), not NAD+; the studies comparing it with NAD+ IV are small and company-sponsored
−The kit showed 'more stock coming soon' at the time of research, so availability is not reliable
−The site does not name the telehealth medical group or the dispensing 503A pharmacy
Read the full Niagen Plus review →

Effecty vs Niagen Plus — FAQ

Is Effecty better than Niagen Plus?

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Effecty scores higher overall in our independent evaluation (66.8/100 vs 64.7/100), leading on value, experience, product range. Niagen Plus comes out ahead on trust & safety, reputation.

Is Effecty or Niagen Plus cheaper?

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Effecty has the lower starting price (from $55/mo vs $149/mo for Niagen Plus). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Effecty and Niagen Plus both offer?

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Both platforms treat Longevity & Peptides. Effecty covers 4 treatment categories total and Niagen Plus covers 1.

Still deciding?

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