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Effecty vs Paloma Health: Which Is Better?

Head-to-head comparison of Effecty and Paloma Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Effecty scores higher overall in our independent evaluation (66.8/100 vs 57.7/100), leading on trust & safety, value, experience, product range. Paloma Health has the lower entry price (from $20/mo vs $55/mo), so the better value depends on which treatment you need.

67

New York-based cash-pay telehealth brand selling compounded GLP-1s, longevity injectables (NAD+, sermorelin, glutathione) and estradiol HRT with no membership fee and published tiered pricing.

Visit Effecty
58

A niche telehealth brand built specifically around hypothyroidism and Hashimoto's care, pairing at-home lab testing with endocrinology-informed treatment.

Visit Paloma Health

Score Breakdown

DimensionEffectyPaloma Health
Overall Score66.8/100 ✓57.7/100
Trust & Safety30%60/100 ✓58/100
Value25%76/100 ✓62/100
Experience20%72/100 ✓55/100
Product Range15%66/100 ✓55/100
Reputation10%55/10055/100

At a Glance

Founded20242018
HeadquartersNew York, NYNew York, NY
Publicly tradedNoNo
Treatment categories42
Treatments listed93
Starting price$55/mo$20/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEffectyPaloma Health
Hormone Therapy$55–$180
Estradiol (tablet, cream or patch) + Progesterone
$20
Thyroid Care Membership

Effecty

+No membership fee, and prices are published per product and don't change with dose (semaglutide $130–$170/mo, tirzepatide $190–$235/mo)
+Card is held, not charged, until a prescription is written; shipping is free and expedited
+4.6/5 on Trustpilot across ~1,300 reviews, most citing fast support responses
−Only operating since November 2024; BBB rating is B with three closed complaints
−Visits are chat-only, and the compounding pharmacies are not named on the site
−Lowest advertised prices require 12-month prepayment; month-to-month runs 25–30% higher
Read the full Effecty review →

Paloma Health

+Narrow clinical focus on hypothyroidism/Hashimoto's with endocrinologist-informed care teams and integrated at-home lab testing, nutritionist visits, and medication management in one program.
+Transparent flat membership pricing ($20/mo billed $240/yr) that bundles two test kits and two visits per year.
+One of the only brands to specialize specifically in DTC thyroid care rather than treating it as one line item among many.
−Trustpilot rating is weak (2.6/5, though based on a very small sample of 4 reviews) with recurring complaints of care that didn't match advertised 'integrative'/'holistic' positioning.
−At least one reported case of a patient with clearly abnormal labs (TSH of 58) alleging the prescribing clinician disregarded their reported symptoms before prescribing a medication that caused adverse reactions — a serious quality-of-care concern for a specialty-clinical brand.
−Reviewers report membership fees and per-visit charges stacking in ways that felt like hidden costs.
Read the full Paloma Health review →

Effecty vs Paloma Health — FAQ

Is Effecty better than Paloma Health?

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Effecty scores higher overall in our independent evaluation (66.8/100 vs 57.7/100), leading on trust & safety, value, experience, product range. Paloma Health has the lower entry price (from $20/mo vs $55/mo), so the better value depends on which treatment you need.

Is Effecty or Paloma Health cheaper?

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Paloma Health has the lower starting price (from $20/mo vs $55/mo for Effecty). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Effecty and Paloma Health both offer?

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Both platforms treat Hormone Therapy. Effecty covers 4 treatment categories total and Paloma Health covers 2.

Still deciding?

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