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Enhance.MD vs Evolve Telemedicine: Which Is Better?

Head-to-head comparison of Enhance.MD and Evolve Telemedicine based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 55.3/100), leading on trust & safety, value, experience, reputation. Evolve Telemedicine comes out ahead on product range. Evolve Telemedicine has the lower entry price (from $149.99/mo vs $169/mo), so the better value depends on which treatment you need.

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

Visit Enhance.MD

A small concierge-style telehealth operator selling compounded hormone, weight-loss, and wellness therapies through a paid membership.

Visit Evolve Telemedicine

Score Breakdown

DimensionEnhance.MDEvolve Telemedicine
Overall Score66.9/100 ✓55.3/100
Trust & Safety30%76/100 ✓55/100
Value25%60/100 ✓48/100
Experience20%68/100 ✓60/100
Product Range15%60/10065/100 ✓
Reputation10%65/100 ✓50/100

At a Glance

Founded2019—
HeadquartersSan Diego, CABloomfield Hills, MI
Publicly tradedNoNo
Treatment categories23
Treatments listed55
Starting price$169/mo$149.99/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDEvolve Telemedicine
Weight Loss / GLP-1$169
Microdose Tirzepatide
$400–$600
Compounded Semaglutide

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

Evolve Telemedicine

+Broad concierge-style hormone and wellness menu (BHRT, TRT, thyroid support, peptide therapy, GLP-1 weight loss, sexual wellness, hair) under one membership with a free initial consult.
+Reports (per prior research, not independently verified on-site) shipping compounded medications to patients in all 50 states.
+A majority of Trustpilot reviewers (78% five-star) describe knowledgeable, thorough clinical staff.
−Reviewers report medication price increases of 200-300% within a few months of enrolling, with claims that comparable prescriptions cost significantly less elsewhere.
−Trustpilot sample is small (54 reviews) — too limited to draw strong reputational conclusions despite the 4.1 average.
−Lab result and refill turnaround delays are a recurring complaint, with patients told to request refills 20-25 days in advance to avoid running out.
Read the full Evolve Telemedicine review →

Enhance.MD vs Evolve Telemedicine — FAQ

Is Enhance.MD better than Evolve Telemedicine?

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Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 55.3/100), leading on trust & safety, value, experience, reputation. Evolve Telemedicine comes out ahead on product range. Evolve Telemedicine has the lower entry price (from $149.99/mo vs $169/mo), so the better value depends on which treatment you need.

Is Enhance.MD or Evolve Telemedicine cheaper?

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Evolve Telemedicine has the lower starting price (from $149.99/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and Evolve Telemedicine both offer?

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Both platforms treat Weight Loss / GLP-1. Enhance.MD covers 2 treatment categories total and Evolve Telemedicine covers 3.

Still deciding?