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Enhance.MD vs HealthRX: Which Is Better?

Head-to-head comparison of Enhance.MD and HealthRX based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 59.3/100), leading on trust & safety, experience, product range, reputation. HealthRX comes out ahead on value. HealthRX has the lower entry price (from $99/mo vs $169/mo), so the better value depends on which treatment you need.

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Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

Visit Enhance.MD
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HealthRX.com is a compounded-GLP-1 telehealth marketplace. It sells semaglutide at $165/mo and tirzepatide at $214/mo at every dose, and backs its program with a weight-loss money-back guarantee.

Visit HealthRX

Score Breakdown

DimensionEnhance.MDHealthRX
Overall Score66.9/100 ✓59.3/100
Trust & Safety30%76/100 ✓55/100
Value25%60/10078/100 ✓
Experience20%68/100 ✓60/100
Product Range15%60/100 ✓45/100
Reputation10%65/100 ✓45/100

At a Glance

Founded20192023
HeadquartersSan Diego, CA—
Publicly tradedNoNo
Treatment categories21
Treatments listed52
Starting price$169/mo$99/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDHealthRX
Weight Loss / GLP-1$169
Microdose Tirzepatide
$99–$165
Compounded Semaglutide

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

HealthRX

+Flat pricing at every dose: semaglutide $165/mo ($149 first month) and tirzepatide $214/mo ($193 first month); about $99/mo semaglutide on a 12-month plan
+Physician review within 24 hours, overnight cold-chain shipping included, and a full refund if not prescribed
+Weight-loss money-back guarantee (reported terms: 16+ weeks on treatment, 10% loss threshold)
−Operating company, headquarters, medical group and dispensing pharmacy are not named; terms reference only a San Diego dispute venue
−Guarantee measurement and refund mechanics are not fully published
−Thin independent review footprint for a brand active since about 2023
Read the full HealthRX review →

Enhance.MD vs HealthRX — FAQ

Is Enhance.MD better than HealthRX?

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Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 59.3/100), leading on trust & safety, experience, product range, reputation. HealthRX comes out ahead on value. HealthRX has the lower entry price (from $99/mo vs $169/mo), so the better value depends on which treatment you need.

Is Enhance.MD or HealthRX cheaper?

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HealthRX has the lower starting price (from $99/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and HealthRX both offer?

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Both platforms treat Weight Loss / GLP-1. Enhance.MD covers 2 treatment categories total and HealthRX covers 1.

Still deciding?

Enhance.MD alternativesHealthRX alternativesTake the Match Quiz