Home›Compare›Enhance.MD vs Healthspan

Enhance.MD vs Healthspan: Which Is Better?

Head-to-head comparison of Enhance.MD and Healthspan based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Healthspan scores higher overall in our independent evaluation (71.3/100 vs 66.9/100), leading on value, experience, product range, reputation. Enhance.MD comes out ahead on trust & safety.

67

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

Visit Enhance.MD
71

Healthspan is a Santa Monica-based longevity clinic built around clinician-guided rapamycin protocols, with add-on hormone, metabolic and brand-name GLP-1 care under a $99/mo membership.

Visit Healthspan

Score Breakdown

DimensionEnhance.MDHealthspan
Overall Score66.9/10071.3/100 ✓
Trust & Safety30%76/100 ✓72/100
Value25%60/10068/100 ✓
Experience20%68/10072/100 ✓
Product Range15%60/10074/100 ✓
Reputation10%65/10072/100 ✓

At a Glance

Founded20192019
HeadquartersSan Diego, CASanta Monica, CA
Publicly tradedNoNo
Treatment categories27
Treatments listed514
Starting price$169/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDHealthspan
Weight Loss / GLP-1$169
Microdose Tirzepatide
$248–$398
Wegovy Pill with Ongoing Care
Longevity & Peptides$169
NAD+ Therapy
$25
Acarbose

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

Healthspan

+Deepest rapamycin-centered longevity formulary we track: oral and topical rapamycin, SGLT2 inhibitors, metformin, acarbose, LDN and methylene blue
+Low entry pricing for core longevity drugs (rapamycin from $64/mo, metformin $27, acarbose $25), shown on the homepage
+Strong patient sentiment: 4.8/5 across ~402 Trustpilot reviews, with a founder who responds personally to negative reviews
−Brand-name GLP-1s require the $99+/mo membership on top of the medication cost ($299/mo Zepbound, $149/mo Wegovy pill)
−Longevity uses of rapamycin, SGLT2 inhibitors and metformin are off-label, and headline claims (e.g., an 8-year average biological-age reduction) are self-reported
−Dispensing pharmacy and medical group are not named on the public site
Read the full Healthspan review →

Enhance.MD vs Healthspan — FAQ

Is Enhance.MD better than Healthspan?

▾

Healthspan scores higher overall in our independent evaluation (71.3/100 vs 66.9/100), leading on value, experience, product range, reputation. Enhance.MD comes out ahead on trust & safety.

Is Enhance.MD or Healthspan cheaper?

▾

Healthspan has the lower starting price (from $25/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and Healthspan both offer?

▾

Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. Enhance.MD covers 2 treatment categories total and Healthspan covers 7.

Still deciding?

Enhance.MD alternativesHealthspan alternativesTake the Match Quiz