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Enhance.MD vs Hone Health: Which Is Better?

Head-to-head comparison of Enhance.MD and Hone Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Hone Health scores higher overall in our independent evaluation (77.5/100 vs 66.9/100), leading on trust & safety, value, experience, product range, reputation.

67

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

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78
Hone Health
Very Good

Hone Health pairs an at-home 50+ biomarker blood panel with physician-directed hormone, weight-loss, and men's/women's health telehealth under a tiered membership model.

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Score Breakdown

DimensionEnhance.MDHone Health
Overall Score66.9/10077.5/100 ✓
Trust & Safety30%76/10078/100 ✓
Value25%60/10070/100 ✓
Experience20%68/10080/100 ✓
Product Range15%60/10085/100 ✓
Reputation10%65/10078/100 ✓

At a Glance

Founded20192020
HeadquartersSan Diego, CANew York, NY
Publicly tradedNoNo
Treatment categories25
Treatments listed56
Starting price$169/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDHone Health
Weight Loss / GLP-1$169
Microdose Tirzepatide
$155–$350
GLP-1 Weight Loss

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

Hone Health

+Biomarker testing (50+ markers) grounds treatment decisions in lab data rather than a simple intake questionnaire
+Broad category range spanning hormone therapy, weight loss, sexual health, and hair loss under one platform
+Large volume of positive patient feedback (4.8/5 across 12,359 Trustpilot reviews), concentrated on physician quality
−Premium membership tier ($155/mo) required to unlock some treatments, which reviewers report wasn't made clear at signup
−Support responsiveness complaints, including same-day appointment cancellations
−Full treatment pricing isn't visible until after the $65 paid assessment
Read the full Hone Health review →

Enhance.MD vs Hone Health — FAQ

Is Enhance.MD better than Hone Health?

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Hone Health scores higher overall in our independent evaluation (77.5/100 vs 66.9/100), leading on trust & safety, value, experience, product range, reputation.

Is Enhance.MD or Hone Health cheaper?

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Hone Health has the lower starting price (from $25/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and Hone Health both offer?

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Both platforms treat Weight Loss / GLP-1. Enhance.MD covers 2 treatment categories total and Hone Health covers 5.

Still deciding?

Enhance.MD alternativesHone Health alternativesTake the Match Quiz