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Enhance.MD vs LifeMD: Which Is Better?

Head-to-head comparison of Enhance.MD and LifeMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

LifeMD scores higher overall in our independent evaluation (68/100 vs 66.9/100), leading on value, experience, product range. Enhance.MD comes out ahead on trust & safety, reputation.

67

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

Visit Enhance.MD
68
LifeMD
Good

Publicly traded telehealth betting big on weight loss, with aggressive GLP-1 pricing and fast-growing subscriber base.

Visit LifeMD

Score Breakdown

DimensionEnhance.MDLifeMD
Overall Score66.9/10068/100 ✓
Trust & Safety30%76/100 ✓65/100
Value25%60/10075/100 ✓
Experience20%68/10070/100 ✓
Product Range15%60/10065/100 ✓
Reputation10%65/100 ✓60/100

At a Glance

Founded20192020
HeadquartersSan Diego, CANew York, NY
Publicly tradedNoYes (LFMD)
Treatment categories26
Treatments listed55
Starting price$169/mo$14/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDLifeMD
Weight Loss / GLP-1$169
Microdose Tirzepatide
$149–$349
Branded Wegovy (oral/injectable)

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

LifeMD

+Novo Nordisk partnership for branded Wegovy pill and subscription program
+Eli Lilly partnership for branded Zepbound access
+Publicly traded with quarterly earnings transparency — 25% revenue growth in 2025
−Compounded GLP-1s discontinued — pivoted to branded medications
−Aggressive marketing draws scrutiny from health professionals
−Narrower treatment range than Hims or Ro
Read the full LifeMD review →

Enhance.MD vs LifeMD — FAQ

Is Enhance.MD better than LifeMD?

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LifeMD scores higher overall in our independent evaluation (68/100 vs 66.9/100), leading on value, experience, product range. Enhance.MD comes out ahead on trust & safety, reputation.

Is Enhance.MD or LifeMD cheaper?

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LifeMD has the lower starting price (from $14/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and LifeMD both offer?

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Both platforms treat Weight Loss / GLP-1. Enhance.MD covers 2 treatment categories total and LifeMD covers 6.

Still deciding?

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