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Enhance.MD vs MadeMed: Which Is Better?

Head-to-head comparison of Enhance.MD and MadeMed based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 57.3/100), leading on trust & safety, experience, reputation. MadeMed comes out ahead on value, product range. MadeMed has the lower entry price (from $30/mo vs $169/mo), so the better value depends on which treatment you need.

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Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

Visit Enhance.MD
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MadeMed is a Houston-registered telehealth brand selling compounded injectable and oral GLP-1s, sermorelin, NAD+ and tadalafil through the Xpedicare provider network.

Visit MadeMed

Score Breakdown

DimensionEnhance.MDMadeMed
Overall Score66.9/100 ✓57.3/100
Trust & Safety30%76/100 ✓55/100
Value25%60/10066/100 ✓
Experience20%68/100 ✓45/100
Product Range15%60/10072/100 ✓
Reputation10%65/100 ✓45/100

At a Glance

Founded2019—
HeadquartersSan Diego, CAHouston, TX
Publicly tradedNoNo
Treatment categories23
Treatments listed57
Starting price$169/mo$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDMadeMed
Weight Loss / GLP-1$169
Microdose Tirzepatide
$99–$199
Compounded Semaglutide (injectable)
Longevity & Peptides$169
NAD+ Therapy
$129–$229
Sermorelin (injectable or oral)

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

MadeMed

+Offers both injectable and oral/sublingual versions of semaglutide, tirzepatide and sermorelin, plus NAD+ as injection or nasal spray
+Operating entity, provider network (Xpedicare) and a partner pharmacy (Red Rock) are named in the terms and About page
+Advertised GLP-1 entry pricing from $99/mo is at the low end of the market
−Product pages showed no pricing or product detail during our research, in a direct fetch or a real browser
−Advertised prices and state coverage (about 40 states) come from brand-issued press releases and can't be verified on-site
−No Trustpilot or other independent patient reviews; public coverage is mostly paid newswire content
Read the full MadeMed review →

Enhance.MD vs MadeMed — FAQ

Is Enhance.MD better than MadeMed?

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Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 57.3/100), leading on trust & safety, experience, reputation. MadeMed comes out ahead on value, product range. MadeMed has the lower entry price (from $30/mo vs $169/mo), so the better value depends on which treatment you need.

Is Enhance.MD or MadeMed cheaper?

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MadeMed has the lower starting price (from $30/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and MadeMed both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. Enhance.MD covers 2 treatment categories total and MadeMed covers 3.

Still deciding?

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