Home›Compare›Enhance.MD vs MangoRx

Enhance.MD vs MangoRx: Which Is Better?

Head-to-head comparison of Enhance.MD and MangoRx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 58/100), leading on trust & safety, experience, reputation. MangoRx comes out ahead on value, product range. MangoRx has the lower entry price (from $50/mo vs $169/mo), so the better value depends on which treatment you need.

67

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

Visit Enhance.MD
58

MangoRx is the Dallas-based men's health telehealth brand of Nasdaq-listed Mangoceuticals, selling compounded ED, hair-loss and oral semaglutide products alongside injectable and oral (Kyzatrex) testosterone.

Visit MangoRx

Score Breakdown

DimensionEnhance.MDMangoRx
Overall Score66.9/100 ✓58/100
Trust & Safety30%76/100 ✓55/100
Value25%60/10062/100 ✓
Experience20%68/100 ✓58/100
Product Range15%60/10066/100 ✓
Reputation10%65/100 ✓45/100

At a Glance

Founded20192021
HeadquartersSan Diego, CADallas, TX
Publicly tradedNoYes (MGRX)
Treatment categories25
Treatments listed55
Starting price$169/mo$50/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDMangoRx
Weight Loss / GLP-1$169
Microdose Tirzepatide
$299
Slim (compounded oral semaglutide ODT)

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

MangoRx

+Injectable TRT program priced at $99/month with doctor visits, lab work and medication included (per February 2026 company release and current site listing)
+Offers a branded FDA-approved oral testosterone option (Kyzatrex-based 'Prime') alongside compounded injectable TRT, which few small men's-health platforms carry
+Public-company SEC disclosures make ownership, pharmacy relationships and finances unusually visible for a brand this size
−Going-concern risk: $228,688 cash on hand at June 30, 2026 against a six-month net loss of $4.7M, per its Q2 2026 10-Q
−Compounded products are filled by Epiq Scripts, a pharmacy majority-owned (52%) by the CEO, a related-party arrangement
−Very small patient base: Q2 2026 revenue of $68,757, down 59% year over year, and only 18 Trustpilot reviews
Read the full MangoRx review →

Enhance.MD vs MangoRx — FAQ

Is Enhance.MD better than MangoRx?

▾

Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 58/100), leading on trust & safety, experience, reputation. MangoRx comes out ahead on value, product range. MangoRx has the lower entry price (from $50/mo vs $169/mo), so the better value depends on which treatment you need.

Is Enhance.MD or MangoRx cheaper?

▾

MangoRx has the lower starting price (from $50/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and MangoRx both offer?

▾

Both platforms treat Weight Loss / GLP-1. Enhance.MD covers 2 treatment categories total and MangoRx covers 5.

Still deciding?

Enhance.MD alternativesMangoRx alternativesTake the Match Quiz