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Enhance.MD vs OrderlyMeds: Which Is Better?

Head-to-head comparison of Enhance.MD and OrderlyMeds based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 54.8/100), leading on trust & safety, value, experience, reputation. OrderlyMeds comes out ahead on product range. OrderlyMeds has the lower entry price (from $74/mo vs $169/mo), so the better value depends on which treatment you need.

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

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55
OrderlyMeds
Below Average

2024-founded compounded GLP-1 telehealth service with low entry pricing and add-on wellness perks, but a below-average Trustpilot track record.

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Score Breakdown

DimensionEnhance.MDOrderlyMeds
Overall Score66.9/100 ✓54.8/100
Trust & Safety30%76/100 ✓55/100
Value25%60/100 ✓58/100
Experience20%68/100 ✓50/100
Product Range15%60/10062/100 ✓
Reputation10%65/100 ✓45/100

At a Glance

Founded20192024
HeadquartersSan Diego, CA—
Publicly tradedNoNo
Treatment categories21
Treatments listed54
Starting price$169/mo$74/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDOrderlyMeds
Weight Loss / GLP-1$169
Microdose Tirzepatide
$74–$149
Compounded Semaglutide

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

OrderlyMeds

+Transparent about which named 503A pharmacies fulfill prescriptions
+Low advertised starter pricing ($74-149/mo) provides an accessible entry point
+Bundled extras (BetterHelp therapy access, Trifecta fitness app, nutrition guides) add value beyond medication
−Starter pricing roughly doubles after the first cycle ($74 to $149, $149 to $299/mo), which can surprise patients
−Trustpilot rating of only 3.6/5 with reports of shipping delays and heat-damaged packages
−A licensed pharmacist has publicly flagged concerns about the company's beyond-use-date prescribing practices
Read the full OrderlyMeds review →

Enhance.MD vs OrderlyMeds — FAQ

Is Enhance.MD better than OrderlyMeds?

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Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 54.8/100), leading on trust & safety, value, experience, reputation. OrderlyMeds comes out ahead on product range. OrderlyMeds has the lower entry price (from $74/mo vs $169/mo), so the better value depends on which treatment you need.

Is Enhance.MD or OrderlyMeds cheaper?

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OrderlyMeds has the lower starting price (from $74/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and OrderlyMeds both offer?

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Both platforms treat Weight Loss / GLP-1. Enhance.MD covers 2 treatment categories total and OrderlyMeds covers 1.

Still deciding?