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Enhance.MD vs Rex MD: Which Is Better?

Head-to-head comparison of Enhance.MD and Rex MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Rex MD scores higher overall in our independent evaluation (72.2/100 vs 66.9/100), leading on trust & safety, value, product range, reputation.

67

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

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72
Rex MD
Good

Rex MD is a men's-health telehealth brand — owned by publicly traded LifeMD — covering ED, premature ejaculation, TRT, hair loss, and GLP-1 treatment.

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Score Breakdown

DimensionEnhance.MDRex MD
Overall Score66.9/10072.2/100 ✓
Trust & Safety30%76/10078/100 ✓
Value25%60/10065/100 ✓
Experience20%68/10068/100
Product Range15%60/10078/100 ✓
Reputation10%65/10072/100 ✓

At a Glance

Founded20192019
HeadquartersSan Diego, CANew York, NY
Publicly tradedNoNo
Treatment categories25
Treatments listed56
Starting price$169/mo$2/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDRex MD
Weight Loss / GLP-1$169
Microdose Tirzepatide
$199–$399
GLP-1 Weight Loss

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

Rex MD

+Backed by LifeMD, a publicly traded parent company, giving it more financial and compliance infrastructure than an independent startup
+Strong Trustpilot rating (4.7/5, 5,259 reviews) with consistent praise for customer service staff
+Wide medication range across ED, premature ejaculation, TRT, hair loss, and GLP-1s under one account
−Recurring patient complaints about surprise auto-renewal charges not clearly disclosed at checkout
−Shipping and fulfillment issues reported, including incorrect dosing and underfilled vials
−Headline 'as low as $2/dose' pricing is a teaser rate; full pricing isn't shown until after intake
Read the full Rex MD review →

Enhance.MD vs Rex MD — FAQ

Is Enhance.MD better than Rex MD?

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Rex MD scores higher overall in our independent evaluation (72.2/100 vs 66.9/100), leading on trust & safety, value, product range, reputation.

Is Enhance.MD or Rex MD cheaper?

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Rex MD has the lower starting price (from $2/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and Rex MD both offer?

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Both platforms treat Weight Loss / GLP-1. Enhance.MD covers 2 treatment categories total and Rex MD covers 5.

Still deciding?

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