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Enhance.MD vs Shed: Which Is Better?

Head-to-head comparison of Enhance.MD and Shed based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Shed scores higher overall in our independent evaluation (67/100 vs 66.9/100), leading on value, experience, product range. Enhance.MD comes out ahead on trust & safety, reputation.

67

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

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67
Shed
Good

Weight loss, hair loss, and longevity telehealth with multiple GLP-1 delivery formats including drops, lozenges, and oral tablets.

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Score Breakdown

DimensionEnhance.MDShed
Overall Score66.9/10067/100 ✓
Trust & Safety30%76/100 ✓60/100
Value25%60/10070/100 ✓
Experience20%68/10070/100 ✓
Product Range15%60/10072/100 ✓
Reputation10%65/100 ✓62/100

At a Glance

Founded20192022
HeadquartersSan Diego, CAGilbert, AZ
Publicly tradedNoNo
Treatment categories23
Treatments listed513
Starting price$169/mo$43/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDShed
Weight Loss / GLP-1$169
Microdose Tirzepatide
$115
Naltrexone + Bupropion Capsules
Longevity & Peptides$169
NAD+ Therapy
$115
MIC + B12 Injections

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

Shed

+Widest variety of GLP-1 delivery formats: injections, drops, lozenges, and oral tablets
+Both compounded and brand-name GLP-1 options (Wegovy, Zepbound) available
+10% body weight loss guarantee or money back
−Two-month minimum commitment before cancellation allowed
−Cash-pay only — no insurance accepted
−BBB rating 2.87/5 (not accredited) with billing and cancellation complaints
Read the full Shed review →

Enhance.MD vs Shed — FAQ

Is Enhance.MD better than Shed?

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Shed scores higher overall in our independent evaluation (67/100 vs 66.9/100), leading on value, experience, product range. Enhance.MD comes out ahead on trust & safety, reputation.

Is Enhance.MD or Shed cheaper?

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Shed has the lower starting price (from $43/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and Shed both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. Enhance.MD covers 2 treatment categories total and Shed covers 3.

Still deciding?

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