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Enhance.MD vs System Labs: Which Is Better?

Head-to-head comparison of Enhance.MD and System Labs based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 56.4/100), leading on trust & safety, experience, product range, reputation. System Labs comes out ahead on value. System Labs has the lower entry price (from $89/mo vs $169/mo), so the better value depends on which treatment you need.

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Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

Visit Enhance.MD
56

System Labs is a San Francisco-based telehealth service prescribing compounded NAD+, sermorelin, glutathione and MIC-B12, with half-price first months.

Visit System Labs

Score Breakdown

DimensionEnhance.MDSystem Labs
Overall Score66.9/100 ✓56.4/100
Trust & Safety30%76/100 ✓52/100
Value25%60/10068/100 ✓
Experience20%68/100 ✓55/100
Product Range15%60/100 ✓55/100
Reputation10%65/100 ✓45/100

At a Glance

Founded2019—
HeadquartersSan Diego, CASan Francisco, CA
Publicly tradedNoNo
Treatment categories21
Treatments listed56
Starting price$169/mo$89/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDSystem Labs
Longevity & Peptides$169
NAD+ Therapy
$89
MIC+B12 Injection

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

System Labs

+Every price is posted on the site, including a first-month discount of roughly 40–50%
+Names its main compounding pharmacy (The Pharmacy Hub, Miami) and three board-certified physician advisors
+Both injectable and non-injectable options (NAD+ nasal spray, oral sermorelin)
−Trustpilot removed its business profile for guideline violations, so there is no independent review base
−'20k+ patients' claim is unverified; founding date and company history are not disclosed
−All sales are final once shipped; terms impose binding arbitration and a class-action waiver
Read the full System Labs review →

Enhance.MD vs System Labs — FAQ

Is Enhance.MD better than System Labs?

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Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 56.4/100), leading on trust & safety, experience, product range, reputation. System Labs comes out ahead on value. System Labs has the lower entry price (from $89/mo vs $169/mo), so the better value depends on which treatment you need.

Is Enhance.MD or System Labs cheaper?

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System Labs has the lower starting price (from $89/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and System Labs both offer?

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Both platforms treat Longevity & Peptides. Enhance.MD covers 2 treatment categories total and System Labs covers 1.

Still deciding?

Enhance.MD alternativesSystem Labs alternativesTake the Match Quiz