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Enhance.MD vs TelyRx: Which Is Better?

Head-to-head comparison of Enhance.MD and TelyRx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

TelyRx scores higher overall in our independent evaluation (72.3/100 vs 66.9/100), leading on value, experience, product range. Enhance.MD comes out ahead on trust & safety.

67

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

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72
TelyRx
Good

TelyRx is a publicly listed online pharmacy platform where patients choose from 500+ generic and branded medications and pay a one-time $22 provider-review fee for an asynchronous prescription from an independent, state-licensed clinician.

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Score Breakdown

DimensionEnhance.MDTelyRx
Overall Score66.9/10072.3/100 ✓
Trust & Safety30%76/100 ✓70/100
Value25%60/10072/100 ✓
Experience20%68/10074/100 ✓
Product Range15%60/10080/100 ✓
Reputation10%65/10065/100

At a Glance

Founded2019—
HeadquartersSan Diego, CAClearwater, FL
Publicly tradedNoYes (TSX: TELY)
Treatment categories27
Treatments listed59
Starting price$169/mo$22.99/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDTelyRx
Weight Loss / GLP-1$169
Microdose Tirzepatide
$699.99–$1199.99
Branded Zepbound

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

TelyRx

+Every catalog price is visible before signup; the only clinical fee is a one-time $22 provider review
+Owns its licensed retail pharmacies, so fulfilment and pharmacist support stay in-house
+Very broad catalog (500+ medications) that includes chronic-condition generics such as lisinopril, albuterol and metformin, plus birth control, ED and hair loss
−Branded GLP-1s are priced near list (Wegovy from $1,399.99), well above manufacturer self-pay programs
−Prescribing is questionnaire-only and done by independent providers, with no ongoing clinical relationship
−Recurring complaints about shipping delays and refills charged without the patient's authorization
Read the full TelyRx review →

Enhance.MD vs TelyRx — FAQ

Is Enhance.MD better than TelyRx?

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TelyRx scores higher overall in our independent evaluation (72.3/100 vs 66.9/100), leading on value, experience, product range. Enhance.MD comes out ahead on trust & safety.

Is Enhance.MD or TelyRx cheaper?

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TelyRx has the lower starting price (from $22.99/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and TelyRx both offer?

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Both platforms treat Weight Loss / GLP-1. Enhance.MD covers 2 treatment categories total and TelyRx covers 7.

Still deciding?

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