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Enhance.MD vs Wellorithm: Which Is Better?

Head-to-head comparison of Enhance.MD and Wellorithm based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 54.8/100), leading on trust & safety, experience, reputation. Wellorithm comes out ahead on value, product range.

67

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

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55
Wellorithm
Below Average

Wellorithm is a Miami-based GLP-1 platform that sells compounded semaglutide ($147 first month, then $247 per 28 days) and tirzepatide ($249, then $349), and also lists branded GLP-1s, NAD+, sermorelin and tadalafil.

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Score Breakdown

DimensionEnhance.MDWellorithm
Overall Score66.9/100 ✓54.8/100
Trust & Safety30%76/100 ✓45/100
Value25%60/10068/100 ✓
Experience20%68/100 ✓55/100
Product Range15%60/10065/100 ✓
Reputation10%65/100 ✓35/100

At a Glance

Founded20192025
HeadquartersSan Diego, CAMiami, FL
Publicly tradedNoNo
Treatment categories24
Treatments listed52
Starting price$169/mo$247/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDWellorithm
Weight Loss / GLP-1$169
Microdose Tirzepatide
$247
Compounded Semaglutide (injectable)
Longevity & Peptides$169
NAD+ Therapy
—

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

Wellorithm

+First-month pricing is competitive: compounded semaglutide $147 and tirzepatide $249, with no membership fee and free shipping
+Written weight-loss guarantee: refund of up to four months of fees if a new patient loses less than 10% after 16 adherent weeks (terms apply)
+Broad catalog spanning compounded injectables and tablets, branded GLP-1s, NAD+, sermorelin and tadalafil
−Ongoing prices rise $100 after month one ($247 / $349), and 28-day billing means 13 charges a year
−Medical group and dispensing pharmacy are not named, and the About page shows placeholder 'specialist' profiles with no credentials
−The site advertises a 4.5 Trustpilot score that doesn't match its thin actual Trustpilot profile, which includes a report of an unauthorized $899 charge and a delayed refund
Read the full Wellorithm review →

Enhance.MD vs Wellorithm — FAQ

Is Enhance.MD better than Wellorithm?

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Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 54.8/100), leading on trust & safety, experience, reputation. Wellorithm comes out ahead on value, product range.

Is Enhance.MD or Wellorithm cheaper?

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Enhance.MD has the lower starting price (from $169/mo vs $247/mo for Wellorithm). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and Wellorithm both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. Enhance.MD covers 2 treatment categories total and Wellorithm covers 4.

Still deciding?

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