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Enhance.MD vs Willow: Which Is Better?

Head-to-head comparison of Enhance.MD and Willow based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

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52
Willow
Below Average

Women-focused compounded GLP-1 telehealth brand operating in a limited number of states, tied to a National Advertising Division referral over its marketing claims.

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Score Breakdown

DimensionEnhance.MDWillow
Overall Score66.9/100 ✓51.9/100
Trust & Safety30%76/100 ✓48/100
Value25%60/100 ✓52/100
Experience20%68/100 ✓62/100
Product Range15%60/100 ✓55/100
Reputation10%65/100 ✓38/100

At a Glance

Founded2019—
HeadquartersSan Diego, CA—
Publicly tradedNoNo
Treatment categories22
Treatments listed52
Starting price$169/mo$299/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDWillow
Weight Loss / GLP-1$169
Microdose Tirzepatide
$299
Compounded Semaglutide

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

Willow

+Women-focused positioning with unlimited doctor access included in plan price
+Reviewers highlight responsive, board-certified doctors and simple onboarding
+Some patients report substantial results (e.g., 65 lbs in three months)
−Reportedly referred by the National Advertising Division to state attorneys general (Dec 2025) over advertising claims — unverified independently this cycle, needs manual confirmation
−Service limited to a narrow footprint (reportedly ~12 states), well below most national competitors
−Pricing ($299-399/mo starting) runs higher than several direct compounded-GLP-1 competitors
Read the full Willow review →

Enhance.MD vs Willow — FAQ

Is Enhance.MD better than Willow?

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Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

Is Enhance.MD or Willow cheaper?

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Enhance.MD has the lower starting price (from $169/mo vs $299/mo for Willow). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and Willow both offer?

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Both platforms treat Weight Loss / GLP-1. Enhance.MD covers 2 treatment categories total and Willow covers 2.

Still deciding?