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Enhance.MD vs Wisp: Which Is Better?

Head-to-head comparison of Enhance.MD and Wisp based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Wisp scores higher overall in our independent evaluation (73.6/100 vs 66.9/100), leading on value, experience, product range, reputation. Enhance.MD comes out ahead on trust & safety.

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

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74
Wisp
Good

Async telehealth platform for sexual and reproductive health, prescribing UTI, BV, yeast, herpes, STI, birth control, and menopause treatment at scale with no consult fee.

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Score Breakdown

DimensionEnhance.MDWisp
Overall Score66.9/10073.6/100 ✓
Trust & Safety30%76/100 ✓72/100
Value25%60/10078/100 ✓
Experience20%68/10070/100 ✓
Product Range15%60/10075/100 ✓
Reputation10%65/10072/100 ✓

At a Glance

Founded20192018
HeadquartersSan Diego, CAAustin, TX
Publicly tradedNoNo
Treatment categories24
Treatments listed54
Starting price$169/mo$5/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDWisp
Weight Loss / GLP-1$169
Microdose Tirzepatide
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Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

Wisp

+No consult fee, with async intake and prescriptions typically issued within hours
+Broad service line under one account: UTI, BV, yeast, herpes, STI treatment/prevention (including DoxyPEP), birth control, and menopause care
+Large scale and review base (2M+ patients, 11,496 Trustpilot reviews at 4.1) indicating consistent service delivery
−Recurring reports of patients being charged for prescriptions that were never sent to the pharmacy, paired with difficulty reaching phone support
−Some patients report side effects or mismatched treatment, suggesting async intake screening can miss individual nuance a live visit would catch
−Weight-care and membership pricing are not fully published prior to starting an intake
Read the full Wisp review →

Enhance.MD vs Wisp — FAQ

Is Enhance.MD better than Wisp?

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Wisp scores higher overall in our independent evaluation (73.6/100 vs 66.9/100), leading on value, experience, product range, reputation. Enhance.MD comes out ahead on trust & safety.

Is Enhance.MD or Wisp cheaper?

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Wisp has the lower starting price (from $5/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and Wisp both offer?

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Both platforms treat Weight Loss / GLP-1. Enhance.MD covers 2 treatment categories total and Wisp covers 4.

Still deciding?