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Enhance.MD vs Yucca Health: Which Is Better?

Head-to-head comparison of Enhance.MD and Yucca Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Yucca Health scores higher overall in our independent evaluation (68.3/100 vs 66.9/100), leading on value, experience. Enhance.MD comes out ahead on trust & safety, product range, reputation.

67

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

Visit Enhance.MD
68

Yucca Health is a Beverly Hills-based telehealth platform selling compounded semaglutide and tirzepatide at flat, dose-independent prices, plus compounded NAD+ and sermorelin.

Visit Yucca Health

Score Breakdown

DimensionEnhance.MDYucca Health
Overall Score66.9/10068.3/100 ✓
Trust & Safety30%76/100 ✓64/100
Value25%60/10080/100 ✓
Experience20%68/10072/100 ✓
Product Range15%60/100 ✓58/100
Reputation10%65/100 ✓60/100

At a Glance

Founded20192025
HeadquartersSan Diego, CABeverly Hills, CA
Publicly tradedNoNo
Treatment categories22
Treatments listed54
Starting price$169/mo$125/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEnhance.MDYucca Health
Weight Loss / GLP-1$169
Microdose Tirzepatide
$125–$146
Compounded Semaglutide+ (injectable)
Longevity & Peptides$169
NAD+ Therapy
$158–$215
NAD+ Injection

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

Yucca Health

+Full price grid published before intake: semaglutide $146/mo monthly, $140/mo quarterly or $125/mo on a 6-month prepay; tirzepatide $258, $248 or $225/mo
+Locked pricing covers the whole dose range, so titrating up does not raise the bill; pausing keeps the locked rate
+No separate membership or consultation fee; plans include the provider consult, medication, injection supplies and free 2-day shipping
−Dispensing pharmacies are not named on the public site; they appear only in the patient portal and on the label after ordering
−BBB rating of C+ (not accredited) with five closed complaints; one Trustpilot reviewer reports prepaying six months and receiving three
−About 6% of roughly 1,230 Trustpilot reviews are 1-star, citing lack of results after months of treatment and refund disputes
Read the full Yucca Health review →

Enhance.MD vs Yucca Health — FAQ

Is Enhance.MD better than Yucca Health?

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Yucca Health scores higher overall in our independent evaluation (68.3/100 vs 66.9/100), leading on value, experience. Enhance.MD comes out ahead on trust & safety, product range, reputation.

Is Enhance.MD or Yucca Health cheaper?

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Yucca Health has the lower starting price (from $125/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Enhance.MD and Yucca Health both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. Enhance.MD covers 2 treatment categories total and Yucca Health covers 2.

Still deciding?

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