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He & She MD vs Josie: Which Is Better?

Head-to-head comparison of He & She MD and Josie based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

He & She MD scores higher overall in our independent evaluation (65.3/100 vs 57.6/100), leading on trust & safety, value, experience, product range, reputation.

65

He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.

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58
Josie
Fair

Small menopause-focused telehealth brand selling compounded and branded GLP-1s, microdose GLP-1 maintenance plans and estradiol/progesterone HRT at flat published prices.

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Score Breakdown

DimensionHe & She MDJosie
Overall Score65.3/100 ✓57.6/100
Trust & Safety30%58/100 ✓50/100
Value25%74/100 ✓70/100
Experience20%60/100 ✓58/100
Product Range15%84/100 ✓60/100
Reputation10%48/100 ✓45/100

At a Glance

Founded2025—
HeadquartersNewport Beach, CA—
Publicly tradedNoNo
Treatment categories73
Treatments listed137
Starting price$60/mo$90/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHe & She MDJosie
Weight Loss / GLP-1$99–$199
Compounded Semaglutide (injectable)
$189
Microdose GLP-1 Maintenance (semaglutide or tirzepatide)
Hormone Therapy$119
Testosterone (injection, gel, tablet)
$90–$100
Estradiol Patch or Cream (HRT)
Women's Health——

He & She MD

+Broad catalog covering compounded GLP-1s (injectable and oral), NAD+, sermorelin, glutathione, estradiol/progesterone HRT, testosterone, enclomiphene, hair loss and ED
+Names its dispensing pharmacies and the states where one partner cannot ship sterile compounds
+Low entry pricing on long terms: compounded semaglutide $99/mo on annual prepay, hair loss $79/mo, ED from $10/dose
−Site shows '4.8 Excellent' and 5.0 rating badges while its Trustpilot profile has zero reviews, so the ratings can't be verified
−Most headline prices require 3- to 12-month prepayment; month-to-month semaglutide is $199 and tirzepatide $299
−Platform terms allow a $15 fee per additional consult or lab-result interpretation on top of plan prices
Read the full He & She MD review →

Josie

+Flat pricing at any dose, published before intake: compounded semaglutide $249/mo ($194/mo prepaid annually), tirzepatide $349/mo ($233/mo annually)
+Offers injectable, oral ODT and microdose ($189/mo) GLP-1 formats alongside HRT in one women's-midlife intake
+Names its lead clinician (Dr. Ana Lisa Carr, MD, board-certified in family medicine) and says it serves all 50 states
−FDA warning letter (Feb 20, 2026) for misbranded compounded semaglutide/tirzepatide marketing
−White-label setup: Josie is a trade name of One Eleven Nutrition LLC on the CareValidate platform, and its terms say it doesn't control provider decisions
−An $80 consultation fee applies if a provider approves a plan and the patient declines medication, and filled orders are non-refundable
Read the full Josie review →

He & She MD vs Josie — FAQ

Is He & She MD better than Josie?

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He & She MD scores higher overall in our independent evaluation (65.3/100 vs 57.6/100), leading on trust & safety, value, experience, product range, reputation.

Is He & She MD or Josie cheaper?

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He & She MD has the lower starting price (from $60/mo vs $90/mo for Josie). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do He & She MD and Josie both offer?

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Both platforms treat Weight Loss / GLP-1, Hormone Therapy, Women's Health. He & She MD covers 7 treatment categories total and Josie covers 3.

Still deciding?

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