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Hello Alpha vs Twentyeight Health: Which Is Better?

Head-to-head comparison of Hello Alpha and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 73/100), leading on trust & safety, value, product range. Hello Alpha comes out ahead on experience.

Women's-health-focused telehealth membership, physician co-founded, treating 100+ conditions including hair loss and prescription skincare.

Visit Hello Alpha

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionHello AlphaTwentyeight Health
Overall Score73/10075/100 ✓
Trust & Safety30%75/10076/100 ✓
Value25%74/10080/100 ✓
Experience20%76/100 ✓72/100
Product Range15%65/10072/100 ✓
Reputation10%70/10070/100

At a Glance

Founded20172018
HeadquartersPalo Alto, CABrooklyn, NY
Publicly tradedNoNo
Treatment categories34
Treatments listed57
Starting price$20/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHello AlphaTwentyeight Health
Women's Health$29
Basic Membership
$15–$19.99
Complete Care Membership
Dermatology$20–$40
Rx Acne / Skincare (Tretinoin)
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Hello Alpha

+Physician co-founded (Dr. Mary Jacobson, MD), with over 8,300 Trustpilot reviews averaging 4.3/5 and roughly 81% of recent reviews at 5 stars
+Membership tiers as low as $29/month, with medications priced and shipped separately, across 100+ treatable conditions spanning women's health, hair loss, and dermatology
+Fast provider response times reported by patients, with straightforward online intake
−Intake questionnaires described by some patients as repetitive across visit types
−Some patients report slow follow-up on missing shipments or refill requests
−Support responsiveness is inconsistent for account-access issues, per patient reports
Read the full Hello Alpha review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

Hello Alpha vs Twentyeight Health — FAQ

Is Hello Alpha better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 73/100), leading on trust & safety, value, product range. Hello Alpha comes out ahead on experience.

Is Hello Alpha or Twentyeight Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $20/mo for Hello Alpha). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Hello Alpha and Twentyeight Health both offer?

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Both platforms treat Women's Health, Dermatology. Hello Alpha covers 3 treatment categories total and Twentyeight Health covers 4.

Still deciding?