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Hims & Hers vs Synergy Rx: Which Is Better?

Head-to-head comparison of Hims & Hers and Synergy Rx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Hims & Hers scores higher overall in our independent evaluation (77.5/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

78
Hims & Hers
Very Good

The largest publicly traded D2C telehealth platform, offering treatments across hair loss, ED, mental health, skincare, and weight loss.

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52
Synergy Rx
Below Average

Synergy Rx is a GLP-1 and peptide storefront launched in 2026 on CareValidate's white-label platform. It sells compounded semaglutide and tirzepatide as injections or oral tablets, prescribed through the Lion MD network.

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Score Breakdown

DimensionHims & HersSynergy Rx
Overall Score77.5/100 ✓51.9/100
Trust & Safety30%75/100 ✓48/100
Value25%70/100 ✓60/100
Experience20%85/100 ✓50/100
Product Range15%90/100 ✓58/100
Reputation10%70/100 ✓38/100

At a Glance

Founded20172026
HeadquartersSan Francisco, CA—
Publicly tradedYes (HIMS)No
Treatment categories73
Treatments listed119
Starting price$11/mo$109/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHims & HersSynergy Rx
Weight Loss / GLP-1$149–$299
Branded Wegovy (oral/injectable)
$199
Compounded Semaglutide (injectable)
Sexual Health$11–$44
Tadalafil (generic Cialis)
$275
PT-141 (bremelanotide)

Hims & Hers

+Widest treatment category coverage of any D2C telehealth brand
+Vertically integrated pharmacy keeps costs down and shipping fast
+Publicly traded with transparent financials
−Compounded GLP-1 programs being phased out after Novo Nordisk deal
−Subscription auto-renewal complaints common on Reddit
−Customer support response times vary
Read the full Hims & Hers review →

Synergy Rx

+Offers both injectable and oral-tablet compounded semaglutide and tirzepatide
+Names its four dispensing pharmacies and supervising Lion MD physicians
+Wider peptide menu than sibling storefronts: NAD+, sermorelin, glutathione, B12, PT-141
−Independent review found the intake does not screen for medullary thyroid cancer or MEN2 history (GLP-1 boxed-warning contraindication)
−Pricing is withheld until after the consult on the brand's own site; consult fee is disclosed inconsistently ($59 vs $80)
−Launched in 2026 with no Trustpilot, BBB or patient-review history
Read the full Synergy Rx review →

Hims & Hers vs Synergy Rx — FAQ

Is Hims & Hers better than Synergy Rx?

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Hims & Hers scores higher overall in our independent evaluation (77.5/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

Is Hims & Hers or Synergy Rx cheaper?

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Hims & Hers has the lower starting price (from $11/mo vs $109/mo for Synergy Rx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Hims & Hers and Synergy Rx both offer?

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Both platforms treat Weight Loss / GLP-1, Sexual Health. Hims & Hers covers 7 treatment categories total and Synergy Rx covers 3.

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