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IVY RX vs Synergy Rx: Which Is Better?

Head-to-head comparison of IVY RX and Synergy Rx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

IVY RX scores higher overall in our independent evaluation (64/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

64
IVY RX
Fair

IVY RX is a Miami-based cash-pay telehealth platform, founded by a pharmacist in 2023, selling compounded GLP-1 injections, microdoses and oral melts alongside NAD+, sermorelin, glutathione and B12 injections.

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52
Synergy Rx
Below Average

Synergy Rx is a GLP-1 and peptide storefront launched in 2026 on CareValidate's white-label platform. It sells compounded semaglutide and tirzepatide as injections or oral tablets, prescribed through the Lion MD network.

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Score Breakdown

DimensionIVY RXSynergy Rx
Overall Score64/100 ✓51.9/100
Trust & Safety30%55/100 ✓48/100
Value25%68/100 ✓60/100
Experience20%70/100 ✓50/100
Product Range15%70/100 ✓58/100
Reputation10%60/100 ✓38/100

At a Glance

Founded20232026
HeadquartersMiami, FL—
Publicly tradedNoNo
Treatment categories23
Treatments listed109
Starting price$90/mo$109/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryIVY RXSynergy Rx
Weight Loss / GLP-1$90
Metformin
$199
Compounded Semaglutide (injectable)
Longevity & Peptides$175
Sermorelin Injection
$109
B12 Methylcobalamin

IVY RX

+Large, positive Trustpilot base (4.7/5 across 7,300+ reviews) and replies to 91% of negative reviews
+Multiple GLP-1 formats (weekly injection, microdose, daily oral melts) plus branded Ozempic and Mounjaro
+Broad longevity menu (NAD+, sermorelin, glutathione, MIC-B12) with prices published before intake
−No lab work required before GLP-1 prescribing
−Markets '503B/USP <797>' sourcing, but a reviewer's order shipped from a 503A pharmacy
−BBB rating of C+ with 18 complaints over refill delays and billing after cancellation; refund policy is restrictive
Read the full IVY RX review →

Synergy Rx

+Offers both injectable and oral-tablet compounded semaglutide and tirzepatide
+Names its four dispensing pharmacies and supervising Lion MD physicians
+Wider peptide menu than sibling storefronts: NAD+, sermorelin, glutathione, B12, PT-141
−Independent review found the intake does not screen for medullary thyroid cancer or MEN2 history (GLP-1 boxed-warning contraindication)
−Pricing is withheld until after the consult on the brand's own site; consult fee is disclosed inconsistently ($59 vs $80)
−Launched in 2026 with no Trustpilot, BBB or patient-review history
Read the full Synergy Rx review →

IVY RX vs Synergy Rx — FAQ

Is IVY RX better than Synergy Rx?

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IVY RX scores higher overall in our independent evaluation (64/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

Is IVY RX or Synergy Rx cheaper?

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IVY RX has the lower starting price (from $90/mo vs $109/mo for Synergy Rx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do IVY RX and Synergy Rx both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. IVY RX covers 2 treatment categories total and Synergy Rx covers 3.

Still deciding?

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