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Josie vs MadeMed: Which Is Better?

Head-to-head comparison of Josie and MadeMed based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Josie scores higher overall in our independent evaluation (57.6/100 vs 57.3/100), leading on value, experience. MadeMed comes out ahead on trust & safety, product range. MadeMed has the lower entry price (from $30/mo vs $90/mo), so the better value depends on which treatment you need.

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Josie
Fair

Small menopause-focused telehealth brand selling compounded and branded GLP-1s, microdose GLP-1 maintenance plans and estradiol/progesterone HRT at flat published prices.

Visit Josie
57

MadeMed is a Houston-registered telehealth brand selling compounded injectable and oral GLP-1s, sermorelin, NAD+ and tadalafil through the Xpedicare provider network.

Visit MadeMed

Score Breakdown

DimensionJosieMadeMed
Overall Score57.6/100 ✓57.3/100
Trust & Safety30%50/10055/100 ✓
Value25%70/100 ✓66/100
Experience20%58/100 ✓45/100
Product Range15%60/10072/100 ✓
Reputation10%45/10045/100

At a Glance

Founded——
Headquarters—Houston, TX
Publicly tradedNoNo
Treatment categories33
Treatments listed77
Starting price$90/mo$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryJosieMadeMed
Weight Loss / GLP-1$189
Microdose GLP-1 Maintenance (semaglutide or tirzepatide)
$99–$199
Compounded Semaglutide (injectable)

Josie

+Flat pricing at any dose, published before intake: compounded semaglutide $249/mo ($194/mo prepaid annually), tirzepatide $349/mo ($233/mo annually)
+Offers injectable, oral ODT and microdose ($189/mo) GLP-1 formats alongside HRT in one women's-midlife intake
+Names its lead clinician (Dr. Ana Lisa Carr, MD, board-certified in family medicine) and says it serves all 50 states
−FDA warning letter (Feb 20, 2026) for misbranded compounded semaglutide/tirzepatide marketing
−White-label setup: Josie is a trade name of One Eleven Nutrition LLC on the CareValidate platform, and its terms say it doesn't control provider decisions
−An $80 consultation fee applies if a provider approves a plan and the patient declines medication, and filled orders are non-refundable
Read the full Josie review →

MadeMed

+Offers both injectable and oral/sublingual versions of semaglutide, tirzepatide and sermorelin, plus NAD+ as injection or nasal spray
+Operating entity, provider network (Xpedicare) and a partner pharmacy (Red Rock) are named in the terms and About page
+Advertised GLP-1 entry pricing from $99/mo is at the low end of the market
−Product pages showed no pricing or product detail during our research, in a direct fetch or a real browser
−Advertised prices and state coverage (about 40 states) come from brand-issued press releases and can't be verified on-site
−No Trustpilot or other independent patient reviews; public coverage is mostly paid newswire content
Read the full MadeMed review →

Josie vs MadeMed — FAQ

Is Josie better than MadeMed?

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Josie scores higher overall in our independent evaluation (57.6/100 vs 57.3/100), leading on value, experience. MadeMed comes out ahead on trust & safety, product range. MadeMed has the lower entry price (from $30/mo vs $90/mo), so the better value depends on which treatment you need.

Is Josie or MadeMed cheaper?

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MadeMed has the lower starting price (from $30/mo vs $90/mo for Josie). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Josie and MadeMed both offer?

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Both platforms treat Weight Loss / GLP-1. Josie covers 3 treatment categories total and MadeMed covers 3.

Still deciding?