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Josie vs Rex MD: Which Is Better?

Head-to-head comparison of Josie and Rex MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Rex MD scores higher overall in our independent evaluation (72.2/100 vs 57.6/100), leading on trust & safety, experience, product range, reputation. Josie comes out ahead on value.

Josie

Fair

Small menopause-focused telehealth brand selling compounded and branded GLP-1s, microdose GLP-1 maintenance plans and estradiol/progesterone HRT at flat published prices.

Visit Josie

Rex MD

Good

Rex MD is a men's-health telehealth brand — owned by publicly traded LifeMD — covering ED, premature ejaculation, TRT, hair loss, and GLP-1 treatment.

Visit Rex MD

Score Breakdown

Dimension	Josie	Rex MD
Overall Score	57.6/100	72.2/100 ✓
Trust & Safety30%	50/100	78/100 ✓
Value25%	70/100 ✓	65/100
Experience20%	58/100	68/100 ✓
Product Range15%	60/100	78/100 ✓
Reputation10%	45/100	72/100 ✓

At a Glance

Founded	—	2019
Headquarters	—	New York, NY
Publicly traded	No	No
Treatment categories	3	5
Treatments listed	7	6
Starting price	$90/mo	$2/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

Category	Josie	Rex MD
Hormone Therapy	$90–$100 Estradiol Patch or Cream (HRT)	$79–$199 TRT (cypionate/gel/Clomid/sermorelin)
Weight Loss / GLP-1	$189 Microdose GLP-1 Maintenance (semaglutide or tirzepatide)	$199–$399 GLP-1 Weight Loss

Josie

+Flat pricing at any dose, published before intake: compounded semaglutide $249/mo ($194/mo prepaid annually), tirzepatide $349/mo ($233/mo annually)

+Offers injectable, oral ODT and microdose ($189/mo) GLP-1 formats alongside HRT in one women's-midlife intake

+Names its lead clinician (Dr. Ana Lisa Carr, MD, board-certified in family medicine) and says it serves all 50 states

−FDA warning letter (Feb 20, 2026) for misbranded compounded semaglutide/tirzepatide marketing

−White-label setup: Josie is a trade name of One Eleven Nutrition LLC on the CareValidate platform, and its terms say it doesn't control provider decisions

−An $80 consultation fee applies if a provider approves a plan and the patient declines medication, and filled orders are non-refundable

Read the full Josie review →

Rex MD

+Backed by LifeMD, a publicly traded parent company, giving it more financial and compliance infrastructure than an independent startup

+Strong Trustpilot rating (4.7/5, 5,259 reviews) with consistent praise for customer service staff

+Wide medication range across ED, premature ejaculation, TRT, hair loss, and GLP-1s under one account

−Recurring patient complaints about surprise auto-renewal charges not clearly disclosed at checkout

−Shipping and fulfillment issues reported, including incorrect dosing and underfilled vials

−Headline 'as low as $2/dose' pricing is a teaser rate; full pricing isn't shown until after intake

Read the full Rex MD review →

Josie vs Rex MD — FAQ

Is Josie better than Rex MD?

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Rex MD scores higher overall in our independent evaluation (72.2/100 vs 57.6/100), leading on trust & safety, experience, product range, reputation. Josie comes out ahead on value.

Is Josie or Rex MD cheaper?

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Rex MD has the lower starting price (from $2/mo vs $90/mo for Josie). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Josie and Rex MD both offer?

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Both platforms treat Hormone Therapy, Weight Loss / GLP-1. Josie covers 3 treatment categories total and Rex MD covers 5.

Still deciding?

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