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Josie vs RxSpan MD: Which Is Better?

Head-to-head comparison of Josie and RxSpan MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 57.6/100), leading on trust & safety, product range. Josie comes out ahead on value, experience.

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Josie
Fair

Small menopause-focused telehealth brand selling compounded and branded GLP-1s, microdose GLP-1 maintenance plans and estradiol/progesterone HRT at flat published prices.

Visit Josie
59

RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

Visit RxSpan MD

Score Breakdown

DimensionJosieRxSpan MD
Overall Score57.6/10059.1/100 ✓
Trust & Safety30%50/10060/100 ✓
Value25%70/100 ✓58/100
Experience20%58/100 ✓52/100
Product Range15%60/10078/100 ✓
Reputation10%45/10045/100

At a Glance

Founded—2026
Headquarters—Beverly Hills, CA
Publicly tradedNoNo
Treatment categories34
Treatments listed79
Starting price$90/mo$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryJosieRxSpan MD
Weight Loss / GLP-1$189
Microdose GLP-1 Maintenance (semaglutide or tirzepatide)
$249–$299
Compounded Semaglutide (injection or oral)

Josie

+Flat pricing at any dose, published before intake: compounded semaglutide $249/mo ($194/mo prepaid annually), tirzepatide $349/mo ($233/mo annually)
+Offers injectable, oral ODT and microdose ($189/mo) GLP-1 formats alongside HRT in one women's-midlife intake
+Names its lead clinician (Dr. Ana Lisa Carr, MD, board-certified in family medicine) and says it serves all 50 states
−FDA warning letter (Feb 20, 2026) for misbranded compounded semaglutide/tirzepatide marketing
−White-label setup: Josie is a trade name of One Eleven Nutrition LLC on the CareValidate platform, and its terms say it doesn't control provider decisions
−An $80 consultation fee applies if a provider approves a plan and the patient declines medication, and filled orders are non-refundable
Read the full Josie review →

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

Josie vs RxSpan MD — FAQ

Is Josie better than RxSpan MD?

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RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 57.6/100), leading on trust & safety, product range. Josie comes out ahead on value, experience.

Is Josie or RxSpan MD cheaper?

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RxSpan MD has the lower starting price (from $30/mo vs $90/mo for Josie). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Josie and RxSpan MD both offer?

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Both platforms treat Weight Loss / GLP-1. Josie covers 3 treatment categories total and RxSpan MD covers 4.

Still deciding?

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