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Josie vs Sesame Care: Which Is Better?

Head-to-head comparison of Josie and Sesame Care based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Sesame Care scores higher overall in our independent evaluation (74/100 vs 57.6/100), leading on trust & safety, value, experience, product range, reputation.

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Josie
Fair

Small menopause-focused telehealth brand selling compounded and branded GLP-1s, microdose GLP-1 maintenance plans and estradiol/progesterone HRT at flat published prices.

Visit Josie
74

Pay-per-visit marketplace connecting patients with licensed providers — no subscriptions, transparent per-visit pricing.

Visit Sesame Care

Score Breakdown

DimensionJosieSesame Care
Overall Score57.6/10074/100 ✓
Trust & Safety30%50/10075/100 ✓
Value25%70/10080/100 ✓
Experience20%58/10070/100 ✓
Product Range15%60/10070/100 ✓
Reputation10%45/10070/100 ✓

At a Glance

Founded—2019
Headquarters—New York, NY
Publicly tradedNoNo
Treatment categories36
Treatments listed77
Starting price$90/mo$11/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryJosieSesame Care
Women's Health——
Weight Loss / GLP-1$189
Microdose GLP-1 Maintenance (semaglutide or tirzepatide)
$59–$99
Weight Loss Program (subscription)

Josie

+Flat pricing at any dose, published before intake: compounded semaglutide $249/mo ($194/mo prepaid annually), tirzepatide $349/mo ($233/mo annually)
+Offers injectable, oral ODT and microdose ($189/mo) GLP-1 formats alongside HRT in one women's-midlife intake
+Names its lead clinician (Dr. Ana Lisa Carr, MD, board-certified in family medicine) and says it serves all 50 states
−FDA warning letter (Feb 20, 2026) for misbranded compounded semaglutide/tirzepatide marketing
−White-label setup: Josie is a trade name of One Eleven Nutrition LLC on the CareValidate platform, and its terms say it doesn't control provider decisions
−An $80 consultation fee applies if a provider approves a plan and the patient declines medication, and filled orders are non-refundable
Read the full Josie review →

Sesame Care

+No subscription required — pay-per-visit model
+Transparent pricing shown before booking
+Wide range of specialties available
−No integrated pharmacy
−Less continuity of care than subscriptions
−Provider quality varies in marketplace model
Read the full Sesame Care review →

Josie vs Sesame Care — FAQ

Is Josie better than Sesame Care?

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Sesame Care scores higher overall in our independent evaluation (74/100 vs 57.6/100), leading on trust & safety, value, experience, product range, reputation.

Is Josie or Sesame Care cheaper?

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Sesame Care has the lower starting price (from $11/mo vs $90/mo for Josie). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Josie and Sesame Care both offer?

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Both platforms treat Women's Health, Weight Loss / GLP-1. Josie covers 3 treatment categories total and Sesame Care covers 6.

Still deciding?

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