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Josie vs SkinnyRx: Which Is Better?

Head-to-head comparison of Josie and SkinnyRx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

SkinnyRx scores higher overall in our independent evaluation (57.9/100 vs 57.6/100), leading on experience. Josie comes out ahead on trust & safety, value, product range, reputation. Josie has the lower entry price (from $90/mo vs $199/mo), so the better value depends on which treatment you need.

58
Josie
Fair

Small menopause-focused telehealth brand selling compounded and branded GLP-1s, microdose GLP-1 maintenance plans and estradiol/progesterone HRT at flat published prices.

Visit Josie
58

Cash-pay compounded GLP-1 provider offering five dosing formats, currently facing an FDA warning letter against its parent company.

Visit SkinnyRx

Score Breakdown

DimensionJosieSkinnyRx
Overall Score57.6/10057.9/100 ✓
Trust & Safety30%50/100 ✓45/100
Value25%70/100 ✓68/100
Experience20%58/10078/100 ✓
Product Range15%60/100 ✓55/100
Reputation10%45/100 ✓35/100

At a Glance

Founded——
Headquarters——
Publicly tradedNoNo
Treatment categories31
Treatments listed74
Starting price$90/mo$199/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryJosieSkinnyRx
Weight Loss / GLP-1$189
Microdose GLP-1 Maintenance (semaglutide or tirzepatide)
$199
Semaglutide Injection

Josie

+Flat pricing at any dose, published before intake: compounded semaglutide $249/mo ($194/mo prepaid annually), tirzepatide $349/mo ($233/mo annually)
+Offers injectable, oral ODT and microdose ($189/mo) GLP-1 formats alongside HRT in one women's-midlife intake
+Names its lead clinician (Dr. Ana Lisa Carr, MD, board-certified in family medicine) and says it serves all 50 states
−FDA warning letter (Feb 20, 2026) for misbranded compounded semaglutide/tirzepatide marketing
−White-label setup: Josie is a trade name of One Eleven Nutrition LLC on the CareValidate platform, and its terms say it doesn't control provider decisions
−An $80 consultation fee applies if a provider approves a plan and the patient declines medication, and filled orders are non-refundable
Read the full Josie review →

SkinnyRx

+Five dosing formats (injection, sublingual, tablet) for semaglutide/tirzepatide give patients flexibility
+Large Trustpilot volume (5,390 reviews) at a 4.8 average suggests broad satisfaction
+Reps cited by name in reviews for responsive onboarding guidance
−FDA warning letter reportedly issued to parent company Lean Rx, Inc. (February 2026) — unverified independently this cycle, needs manual confirmation
−Some patients report oral/sublingual formats were ineffective with no visible results
−A reviewer described being required to pay upfront for medication that had no effect
Read the full SkinnyRx review →

Josie vs SkinnyRx — FAQ

Is Josie better than SkinnyRx?

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SkinnyRx scores higher overall in our independent evaluation (57.9/100 vs 57.6/100), leading on experience. Josie comes out ahead on trust & safety, value, product range, reputation. Josie has the lower entry price (from $90/mo vs $199/mo), so the better value depends on which treatment you need.

Is Josie or SkinnyRx cheaper?

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Josie has the lower starting price (from $90/mo vs $199/mo for SkinnyRx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Josie and SkinnyRx both offer?

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Both platforms treat Weight Loss / GLP-1. Josie covers 3 treatment categories total and SkinnyRx covers 1.

Still deciding?

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