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Josie vs TrimRx: Which Is Better?

Head-to-head comparison of Josie and TrimRx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Josie scores higher overall in our independent evaluation (57.6/100 vs 52/100), leading on experience, product range. TrimRx comes out ahead on trust & safety.

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Josie
Fair

Small menopause-focused telehealth brand selling compounded and branded GLP-1s, microdose GLP-1 maintenance plans and estradiol/progesterone HRT at flat published prices.

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52
TrimRx
Below Average

San Diego-based GLP-1 weight loss telehealth offering compounded semaglutide and tirzepatide at $179-349/month.

Visit TrimRx

Score Breakdown

DimensionJosieTrimRx
Overall Score57.6/100 ✓52/100
Trust & Safety30%50/10055/100 ✓
Value25%70/10070/100
Experience20%58/100 ✓45/100
Product Range15%60/100 ✓30/100
Reputation10%45/10045/100

At a Glance

Founded—2024
Headquarters—San Diego, CA
Publicly tradedNoNo
Treatment categories31
Treatments listed78
Starting price$90/mo$179/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryJosieTrimRx
Weight Loss / GLP-1$189
Microdose GLP-1 Maintenance (semaglutide or tirzepatide)
$179–$329
Compounded Semaglutide (Oral/Sublingual)

Josie

+Flat pricing at any dose, published before intake: compounded semaglutide $249/mo ($194/mo prepaid annually), tirzepatide $349/mo ($233/mo annually)
+Offers injectable, oral ODT and microdose ($189/mo) GLP-1 formats alongside HRT in one women's-midlife intake
+Names its lead clinician (Dr. Ana Lisa Carr, MD, board-certified in family medicine) and says it serves all 50 states
−FDA warning letter (Feb 20, 2026) for misbranded compounded semaglutide/tirzepatide marketing
−White-label setup: Josie is a trade name of One Eleven Nutrition LLC on the CareValidate platform, and its terms say it doesn't control provider decisions
−An $80 consultation fee applies if a provider approves a plan and the patient declines medication, and filled orders are non-refundable
Read the full Josie review →

TrimRx

+70-85% savings vs brand-name GLP-1s: semaglutide at $199/mo vs $1,000+ retail
+Not included in FDA's 2025 warning letter wave — clean regulatory record
+Multiple delivery formats: injectable, oral tablet, and sublingual drops
−Branded pages advertise 'In Stock' with a price while the same page states TrimRx does not sell, dispense or ship branded medication and the patient pays a pharmacy directly
−Cancellation difficulties: long phone waits, reports of being hung up on; dedicated JoinChargeback page exists
−Strict no-refund policy once medical intake is submitted, even before medication ships
Read the full TrimRx review →

Josie vs TrimRx — FAQ

Is Josie better than TrimRx?

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Josie scores higher overall in our independent evaluation (57.6/100 vs 52/100), leading on experience, product range. TrimRx comes out ahead on trust & safety.

Is Josie or TrimRx cheaper?

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Josie has the lower starting price (from $90/mo vs $179/mo for TrimRx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Josie and TrimRx both offer?

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Both platforms treat Weight Loss / GLP-1. Josie covers 3 treatment categories total and TrimRx covers 1.

Still deciding?

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