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Josie vs Yucca Health: Which Is Better?

Head-to-head comparison of Josie and Yucca Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Yucca Health scores higher overall in our independent evaluation (68.3/100 vs 57.6/100), leading on trust & safety, value, experience, reputation. Josie comes out ahead on product range. Josie has the lower entry price (from $90/mo vs $125/mo), so the better value depends on which treatment you need.

Josie

Fair

Small menopause-focused telehealth brand selling compounded and branded GLP-1s, microdose GLP-1 maintenance plans and estradiol/progesterone HRT at flat published prices.

Visit Josie

Yucca Health

Good

Yucca Health is a Beverly Hills-based telehealth platform selling compounded semaglutide and tirzepatide at flat, dose-independent prices, plus compounded NAD+ and sermorelin.

Visit Yucca Health

Score Breakdown

Dimension	Josie	Yucca Health
Overall Score	57.6/100	68.3/100 ✓
Trust & Safety30%	50/100	64/100 ✓
Value25%	70/100	80/100 ✓
Experience20%	58/100	72/100 ✓
Product Range15%	60/100 ✓	58/100
Reputation10%	45/100	60/100 ✓

At a Glance

Founded	—	2025
Headquarters	—	Beverly Hills, CA
Publicly traded	No	No
Treatment categories	3	2
Treatments listed	7	4
Starting price	$90/mo	$125/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

Category	Josie	Yucca Health
Weight Loss / GLP-1	$189 Microdose GLP-1 Maintenance (semaglutide or tirzepatide)	$125–$146 Compounded Semaglutide+ (injectable)

Josie

+Flat pricing at any dose, published before intake: compounded semaglutide $249/mo ($194/mo prepaid annually), tirzepatide $349/mo ($233/mo annually)

+Offers injectable, oral ODT and microdose ($189/mo) GLP-1 formats alongside HRT in one women's-midlife intake

+Names its lead clinician (Dr. Ana Lisa Carr, MD, board-certified in family medicine) and says it serves all 50 states

−FDA warning letter (Feb 20, 2026) for misbranded compounded semaglutide/tirzepatide marketing

−White-label setup: Josie is a trade name of One Eleven Nutrition LLC on the CareValidate platform, and its terms say it doesn't control provider decisions

−An $80 consultation fee applies if a provider approves a plan and the patient declines medication, and filled orders are non-refundable

Read the full Josie review →

Yucca Health

+Full price grid published before intake: semaglutide $146/mo monthly, $140/mo quarterly or $125/mo on a 6-month prepay; tirzepatide $258, $248 or $225/mo

+Locked pricing covers the whole dose range, so titrating up does not raise the bill; pausing keeps the locked rate

+No separate membership or consultation fee; plans include the provider consult, medication, injection supplies and free 2-day shipping

−Dispensing pharmacies are not named on the public site; they appear only in the patient portal and on the label after ordering

−BBB rating of C+ (not accredited) with five closed complaints; one Trustpilot reviewer reports prepaying six months and receiving three

−About 6% of roughly 1,230 Trustpilot reviews are 1-star, citing lack of results after months of treatment and refund disputes

Read the full Yucca Health review →

Josie vs Yucca Health — FAQ

Is Josie better than Yucca Health?

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Is Josie or Yucca Health cheaper?

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Josie has the lower starting price (from $90/mo vs $125/mo for Yucca Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Josie and Yucca Health both offer?

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Both platforms treat Weight Loss / GLP-1. Josie covers 3 treatment categories total and Yucca Health covers 2.

Still deciding?

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