Home›Compare›MadeMed vs Niagen Plus

MadeMed vs Niagen Plus: Which Is Better?

Head-to-head comparison of MadeMed and Niagen Plus based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 57.3/100), leading on trust & safety, value, experience, reputation. MadeMed comes out ahead on product range. MadeMed has the lower entry price (from $30/mo vs $149/mo), so the better value depends on which treatment you need.

57

MadeMed is a Houston-registered telehealth brand selling compounded injectable and oral GLP-1s, sermorelin, NAD+ and tadalafil through the Xpedicare provider network.

Visit MadeMed
65

Prescription-only telehealth program from Nasdaq-listed Niagen Bioscience (formerly ChromaDex) selling an at-home injection kit of nicotinamide riboside (NR), an NAD+ precursor, rather than NAD+ itself.

Visit Niagen Plus

Score Breakdown

DimensionMadeMedNiagen Plus
Overall Score57.3/10064.7/100 ✓
Trust & Safety30%55/10078/100 ✓
Value25%66/10070/100 ✓
Experience20%45/10058/100 ✓
Product Range15%72/100 ✓36/100
Reputation10%45/10068/100 ✓

At a Glance

Founded—2024
HeadquartersHouston, TXLos Angeles, CA
Publicly tradedNoYes (NAGE)
Treatment categories31
Treatments listed71
Starting price$30/mo$149/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryMadeMedNiagen Plus
Longevity & Peptides$129–$229
Sermorelin (injectable or oral)
$149
Niagen At-Home Injection Kit (NR chloride 500 mg, ~28 days)

MadeMed

+Offers both injectable and oral/sublingual versions of semaglutide, tirzepatide and sermorelin, plus NAD+ as injection or nasal spray
+Operating entity, provider network (Xpedicare) and a partner pharmacy (Red Rock) are named in the terms and About page
+Advertised GLP-1 entry pricing from $99/mo is at the low end of the market
−Product pages showed no pricing or product detail during our research, in a direct fetch or a real browser
−Advertised prices and state coverage (about 40 states) come from brand-issued press releases and can't be verified on-site
−No Trustpilot or other independent patient reviews; public coverage is mostly paid newswire content
Read the full MadeMed review →

Niagen Plus

+Backed by a public company with 25+ years of NAD+-precursor research; it holds the patent on the active ingredient (Niagen NRCl)
+Compounded by a 503B outsourcing facility (FDA-registered, cGMP) rather than a patient-specific 503A lab alone
+Flat, published $149 kit price includes the provider consult, a ~28-day supply, supplies and free Next Day Air shipping
−Only one product, and it is NR (an NAD+ precursor), not NAD+; the studies comparing it with NAD+ IV are small and company-sponsored
−The kit showed 'more stock coming soon' at the time of research, so availability is not reliable
−The site does not name the telehealth medical group or the dispensing 503A pharmacy
Read the full Niagen Plus review →

MadeMed vs Niagen Plus — FAQ

Is MadeMed better than Niagen Plus?

▾

Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 57.3/100), leading on trust & safety, value, experience, reputation. MadeMed comes out ahead on product range. MadeMed has the lower entry price (from $30/mo vs $149/mo), so the better value depends on which treatment you need.

Is MadeMed or Niagen Plus cheaper?

▾

MadeMed has the lower starting price (from $30/mo vs $149/mo for Niagen Plus). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do MadeMed and Niagen Plus both offer?

▾

Both platforms treat Longevity & Peptides. MadeMed covers 3 treatment categories total and Niagen Plus covers 1.

Still deciding?

MadeMed alternativesNiagen Plus alternativesTake the Match Quiz