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Measured vs Synergy Rx: Which Is Better?

Head-to-head comparison of Measured and Synergy Rx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Measured scores higher overall in our independent evaluation (73/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

73

Measured is a New York-based, Y Combinator-backed weight-loss telehealth platform that prescribes branded and compounded GLP-1s, handles insurance prior authorizations, and adds dietitian counseling.

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52
Synergy Rx
Below Average

Synergy Rx is a GLP-1 and peptide storefront launched in 2026 on CareValidate's white-label platform. It sells compounded semaglutide and tirzepatide as injections or oral tablets, prescribed through the Lion MD network.

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Score Breakdown

DimensionMeasuredSynergy Rx
Overall Score73/100 ✓51.9/100
Trust & Safety30%72/100 ✓48/100
Value25%74/100 ✓60/100
Experience20%76/100 ✓50/100
Product Range15%74/100 ✓58/100
Reputation10%66/100 ✓38/100

At a Glance

Founded20212026
HeadquartersNew York, NY—
Publicly tradedNoNo
Treatment categories23
Treatments listed119
Starting price$79/mo$109/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryMeasuredSynergy Rx
Weight Loss / GLP-1$119
Compounded Semaglutide
$199
Compounded Semaglutide (injectable)
Longevity & Peptides$79–$99
GLP-1 Microdose (semaglutide or tirzepatide)
$109
B12 Methylcobalamin

Measured

+Handles insurance benefit checks and prior authorizations for branded GLP-1s, and also offers cash pay (Wegovy pill $149–299, Zepbound $299–449 plus membership)
+Registered Dietitian nutrition counseling available and usually billed to the patient's insurance
+Strong review record: 4.9/5 across about 600 Trustpilot reviews, with only 2% 1-star
−Available in only 26 states and only to adults aged 18–65
−Branded programs stack a monthly membership ($49 promotional, $129 list) on top of separately billed medication
−No refunds once a billing period has started, including for side effects or intolerance
Read the full Measured review →

Synergy Rx

+Offers both injectable and oral-tablet compounded semaglutide and tirzepatide
+Names its four dispensing pharmacies and supervising Lion MD physicians
+Wider peptide menu than sibling storefronts: NAD+, sermorelin, glutathione, B12, PT-141
−Independent review found the intake does not screen for medullary thyroid cancer or MEN2 history (GLP-1 boxed-warning contraindication)
−Pricing is withheld until after the consult on the brand's own site; consult fee is disclosed inconsistently ($59 vs $80)
−Launched in 2026 with no Trustpilot, BBB or patient-review history
Read the full Synergy Rx review →

Measured vs Synergy Rx — FAQ

Is Measured better than Synergy Rx?

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Measured scores higher overall in our independent evaluation (73/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

Is Measured or Synergy Rx cheaper?

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Measured has the lower starting price (from $79/mo vs $109/mo for Synergy Rx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Measured and Synergy Rx both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. Measured covers 2 treatment categories total and Synergy Rx covers 3.

Still deciding?

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