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myLAB Box vs Twentyeight Health: Which Is Better?

Head-to-head comparison of myLAB Box and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 59.7/100), leading on trust & safety, value, experience, product range, reputation.

60

At-home lab testing company selling mail-in STD panels and wellness/fertility tests, with a free physician consultation and local-pharmacy prescription for positive results.

Visit myLAB Box
75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionmyLAB BoxTwentyeight Health
Overall Score59.7/10075/100 ✓
Trust & Safety30%64/10076/100 ✓
Value25%62/10080/100 ✓
Experience20%52/10072/100 ✓
Product Range15%60/10072/100 ✓
Reputation10%56/10070/100 ✓

At a Glance

Founded20142018
HeadquartersLos Angeles, CABrooklyn, NY
Publicly tradedNoNo
Treatment categories34
Treatments listed47
Starting price$99/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategorymyLAB BoxTwentyeight Health
Sexual Health$209
Uber Box (8-Panel STD Test)
—
Women's Health$259
Women's Health + Fertility Test
$15–$19.99
Complete Care Membership

myLAB Box

+Per-test prices are published openly without an account or intake form
+Positive STD results include a free phone consult with a physician licensed in the customer's state, who can prescribe to a local pharmacy
+Broad catalog (50+ tests) including multi-infection panels up to 14 pathogens (HIV, syphilis, herpes, HPV, Mycoplasma genitalium)
−Recurring Trustpilot complaints about results arriving well after the advertised turnaround, in some cases weeks
−No refunds once samples reach the lab, including when customers cite processing delays
−Comprehensive panels are expensive (14-panel Total Box $379-$409) relative to in-person clinic testing
Read the full myLAB Box review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

myLAB Box vs Twentyeight Health — FAQ

Is myLAB Box better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 59.7/100), leading on trust & safety, value, experience, product range, reputation.

Is myLAB Box or Twentyeight Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $99/mo for myLAB Box). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do myLAB Box and Twentyeight Health both offer?

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Both platforms treat Sexual Health, Women's Health. myLAB Box covers 3 treatment categories total and Twentyeight Health covers 4.

Still deciding?

myLAB Box alternativesTwentyeight Health alternativesTake the Match Quiz