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MyMenopauseRx vs Twentyeight Health: Which Is Better?

Head-to-head comparison of MyMenopauseRx and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 61.3/100), leading on trust & safety, value, experience, product range, reputation.

61

Gynecologist-founded virtual menopause practice that bills most commercial insurance or charges $150 per self-pay visit, prescribing FDA-approved HRT, non-hormonal therapy and branded GLP-1s to local pharmacies.

Visit MyMenopauseRx
75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionMyMenopauseRxTwentyeight Health
Overall Score61.3/10075/100 ✓
Trust & Safety30%74/10076/100 ✓
Value25%58/10080/100 ✓
Experience20%58/10072/100 ✓
Product Range15%50/10072/100 ✓
Reputation10%55/10070/100 ✓

At a Glance

Founded20212018
HeadquartersChicago area, ILBrooklyn, NY
Publicly tradedNoNo
Treatment categories34
Treatments listed37
Starting price$150/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryMyMenopauseRxTwentyeight Health
Women's Health$150
Virtual Menopause Visit (self-pay)
$15–$19.99
Complete Care Membership
Weight Loss / GLP-1——

MyMenopauseRx

+Founder and clinicians are named, and most hold Menopause Society certification (MSCP); patients can keep the same clinician
+In-network with major commercial plans, so many insured patients pay only a copay; $150 flat self-pay rate otherwise
+Prescribes FDA-approved therapies to the patient's local pharmacy, and labs can be ordered on demand at discounted self-pay rates
−No cash-pay medication pricing; the cost of HRT or branded GLP-1s depends on the patient's pharmacy and insurance
−Doesn't accept Medicare, Medicaid or HMO plans, and testosterone is offered only in Illinois
−Very thin public reviews (Trustpilot 3.3/5 on 4), including complaints of rushed visits and repeated charges
Read the full MyMenopauseRx review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

MyMenopauseRx vs Twentyeight Health — FAQ

Is MyMenopauseRx better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 61.3/100), leading on trust & safety, value, experience, product range, reputation.

Is MyMenopauseRx or Twentyeight Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $150/mo for MyMenopauseRx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do MyMenopauseRx and Twentyeight Health both offer?

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Both platforms treat Women's Health, Weight Loss / GLP-1. MyMenopauseRx covers 3 treatment categories total and Twentyeight Health covers 4.

Still deciding?

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