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Natural Cycles vs Twentyeight Health: Which Is Better?

Head-to-head comparison of Natural Cycles and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 67.4/100), leading on trust & safety, value, product range, reputation. Natural Cycles has the lower entry price (from $12.5/mo vs $15/mo), so the better value depends on which treatment you need.

67

FDA-cleared, hormone-free digital contraceptive that uses temperature data from a thermometer or wearable to flag fertile days; it involves no clinician or prescription.

Visit Natural Cycles
75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionNatural CyclesTwentyeight Health
Overall Score67.4/10075/100 ✓
Trust & Safety30%70/10076/100 ✓
Value25%76/10080/100 ✓
Experience20%72/10072/100
Product Range15%45/10072/100 ✓
Reputation10%62/10070/100 ✓

At a Glance

Founded20132018
HeadquartersStockholm, SwedenBrooklyn, NY
Publicly tradedNoNo
Treatment categories14
Treatments listed17
Starting price$12.5/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryNatural CyclesTwentyeight Health
Women's Health$12.5
NC° Birth Control (annual plan incl. NC° Band)
$15–$19.99
Complete Care Membership

Natural Cycles

+Only FDA-cleared digital contraceptive (Class II De Novo, 2018), with no hormones or side effects
+Low all-in cost: about $150/year including the NC° Band wearable, HSA/FSA-eligible
+Works with existing wearables (Oura, Apple Watch Series 8+, Garmin) and switches between contraception, conception, pregnancy, postpartum and perimenopause modes at no extra charge
−Typical-use effectiveness is 93%, below IUDs and implants, and depends on daily measurement and abstaining or using protection on fertile days
−No clinician involvement or prescription options; not a substitute for a birth-control prescriber
−December 2025 class action alleges reproductive-health data was shared with third-party trackers without consent
Read the full Natural Cycles review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

Natural Cycles vs Twentyeight Health — FAQ

Is Natural Cycles better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 67.4/100), leading on trust & safety, value, product range, reputation. Natural Cycles has the lower entry price (from $12.5/mo vs $15/mo), so the better value depends on which treatment you need.

Is Natural Cycles or Twentyeight Health cheaper?

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Natural Cycles has the lower starting price (from $12.5/mo vs $15/mo for Twentyeight Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Natural Cycles and Twentyeight Health both offer?

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Both platforms treat Women's Health. Natural Cycles covers 1 treatment category total and Twentyeight Health covers 4.

Still deciding?

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