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Niagen Plus vs Oak Longevity: Which Is Better?

Head-to-head comparison of Niagen Plus and Oak Longevity based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 60.3/100), leading on trust & safety, value, reputation. Oak Longevity comes out ahead on experience, product range. Oak Longevity has the lower entry price (from $79/mo vs $149/mo), so the better value depends on which treatment you need.

Niagen Plus

Fair

Prescription-only telehealth program from Nasdaq-listed Niagen Bioscience (formerly ChromaDex) selling an at-home injection kit of nicotinamide riboside (NR), an NAD+ precursor, rather than NAD+ itself.

Visit Niagen Plus

Oak Longevity

Fair

Oak Longevity ('Oak Loves You') is a small cash-pay telehealth brand selling compounded GLP-1s, ED medication and NAD+/sermorelin. Headline prices require multi-month plans, and orders become non-refundable once sent to the pharmacy.

Visit Oak Longevity

Score Breakdown

Dimension	Niagen Plus	Oak Longevity
Overall Score	64.7/100 ✓	60.3/100
Trust & Safety30%	78/100 ✓	55/100
Value25%	70/100 ✓	66/100
Experience20%	58/100	64/100 ✓
Product Range15%	36/100	62/100 ✓
Reputation10%	68/100 ✓	52/100

At a Glance

Founded	2024	2024
Headquarters	Los Angeles, CA	—
Publicly traded	Yes (NAGE)	No
Treatment categories	1	3
Treatments listed	1	5
Starting price	$149/mo	$79/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

Category	Niagen Plus	Oak Longevity
Longevity & Peptides	$149 Niagen At-Home Injection Kit (NR chloride 500 mg, ~28 days)	$99 NAD+ Injections

Niagen Plus

+Backed by a public company with 25+ years of NAD+-precursor research; it holds the patent on the active ingredient (Niagen NRCl)

+Compounded by a 503B outsourcing facility (FDA-registered, cGMP) rather than a patient-specific 503A lab alone

+Flat, published $149 kit price includes the provider consult, a ~28-day supply, supplies and free Next Day Air shipping

−Only one product, and it is NR (an NAD+ precursor), not NAD+; the studies comparing it with NAD+ IV are small and company-sponsored

−The kit showed 'more stock coming soon' at the time of research, so availability is not reliable

−The site does not name the telehealth medical group or the dispensing 503A pharmacy

Read the full Niagen Plus review →

Oak Longevity

+Compounded semaglutide from about $130/mo on multi-month plans, flat across doses

+Positive Trustpilot base (4.4/5, 54 reviews) citing fast approvals and responsive messaging

+Range spans GLP-1s, ED (tadalafil), NAD+ and sermorelin under one account

−Homepage 'from $89/mo' pricing is well below the ~$235/mo (semaglutide) and ~$285/mo (tirzepatide) one-month checkout prices

−Orders become non-refundable once sent to the pharmacy; mandatory arbitration and class-action waiver

−Opaque structure: three legal entity names, a Vancouver, BC BBB registration, and unnamed pharmacies and leadership

Read the full Oak Longevity review →

Niagen Plus vs Oak Longevity — FAQ

Is Niagen Plus better than Oak Longevity?

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Is Niagen Plus or Oak Longevity cheaper?

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Oak Longevity has the lower starting price (from $79/mo vs $149/mo for Niagen Plus). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Niagen Plus and Oak Longevity both offer?

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Both platforms treat Longevity & Peptides. Niagen Plus covers 1 treatment category total and Oak Longevity covers 3.

Still deciding?

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