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Niagen Plus vs Sermorelin.com: Which Is Better?

Head-to-head comparison of Niagen Plus and Sermorelin.com based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 58/100), leading on trust & safety, value, reputation. Sermorelin.com comes out ahead on experience.

65

Prescription-only telehealth program from Nasdaq-listed Niagen Bioscience (formerly ChromaDex) selling an at-home injection kit of nicotinamide riboside (NR), an NAD+ precursor, rather than NAD+ itself.

Visit Niagen Plus
58

Single-product telehealth brand that sells compounded sermorelin as a nightly injection or an under-the-tongue tablet, prescribed by a Florida-based medical group.

Visit Sermorelin.com

Score Breakdown

DimensionNiagen PlusSermorelin.com
Overall Score64.7/100 ✓58/100
Trust & Safety30%78/100 ✓60/100
Value25%70/100 ✓68/100
Experience20%58/10062/100 ✓
Product Range15%36/10036/100
Reputation10%68/100 ✓52/100

At a Glance

Founded2024—
HeadquartersLos Angeles, CASheridan, WY
Publicly tradedYes (NAGE)No
Treatment categories11
Treatments listed12
Starting price$149/mo$149/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryNiagen PlusSermorelin.com
Longevity & Peptides$149
Niagen At-Home Injection Kit (NR chloride 500 mg, ~28 days)
$149–$199
Compounded Sermorelin Injection

Niagen Plus

+Backed by a public company with 25+ years of NAD+-precursor research; it holds the patent on the active ingredient (Niagen NRCl)
+Compounded by a 503B outsourcing facility (FDA-registered, cGMP) rather than a patient-specific 503A lab alone
+Flat, published $149 kit price includes the provider consult, a ~28-day supply, supplies and free Next Day Air shipping
−Only one product, and it is NR (an NAD+ precursor), not NAD+; the studies comparing it with NAD+ IV are small and company-sponsored
−The kit showed 'more stock coming soon' at the time of research, so availability is not reliable
−The site does not name the telehealth medical group or the dispensing 503A pharmacy
Read the full Niagen Plus review →

Sermorelin.com

+All-in pricing shown before intake ($149-$199/mo) covers the physician consult, medication, supplies and free 2-day shipping
+Names its medical group (Wasef Health, PC, Michael Wasef MD) and dispensing pharmacy (SmartScripts / PerfectRx, Flower Mound, TX) on the site
+Offers injectable and sublingual tablet sermorelin at the same price, and says card holds are only charged after physician approval
−Only one drug is offered, so there are no labs, hormone therapy or other longevity treatments
−Operator is an anonymous Wyoming LLC at a registered-agent address; no named founders or clinical leadership beyond the contracted PC
−On-site testimonials name competitors (MaleMD, Eden) in a promotional way that cannot be independently verified
Read the full Sermorelin.com review →

Niagen Plus vs Sermorelin.com — FAQ

Is Niagen Plus better than Sermorelin.com?

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Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 58/100), leading on trust & safety, value, reputation. Sermorelin.com comes out ahead on experience.

Is Niagen Plus or Sermorelin.com cheaper?

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Their entry prices are similar — both start around $149/mo. Real cost depends on the specific treatment: compare the pricing tables on each review, since inclusions like consults, labs, and shipping differ.

What do Niagen Plus and Sermorelin.com both offer?

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Both platforms treat Longevity & Peptides. Niagen Plus covers 1 treatment category total and Sermorelin.com covers 1.

Still deciding?

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