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Niagen Plus vs Syra Rx: Which Is Better?

Head-to-head comparison of Niagen Plus and Syra Rx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 53.5/100), leading on trust & safety, value, experience, reputation. Syra Rx comes out ahead on product range. Syra Rx has the lower entry price (from $30/mo vs $149/mo), so the better value depends on which treatment you need.

65

Prescription-only telehealth program from Nasdaq-listed Niagen Bioscience (formerly ChromaDex) selling an at-home injection kit of nicotinamide riboside (NR), an NAD+ precursor, rather than NAD+ itself.

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54
Syra Rx
Below Average

Syra Rx is a 2026-launched, affiliate-distributed telehealth storefront for compounded GLP-1s, NAD+, sermorelin, tesamorelin and ED treatment, with clinical care outsourced to LocumTele and fulfillment by Rush Pharmacy.

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Score Breakdown

DimensionNiagen PlusSyra Rx
Overall Score64.7/100 ✓53.5/100
Trust & Safety30%78/100 ✓50/100
Value25%70/100 ✓56/100
Experience20%58/100 ✓50/100
Product Range15%36/10070/100 ✓
Reputation10%68/100 ✓40/100

At a Glance

Founded20242026
HeadquartersLos Angeles, CA—
Publicly tradedYes (NAGE)No
Treatment categories13
Treatments listed15
Starting price$149/mo$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryNiagen PlusSyra Rx
Longevity & Peptides$149
Niagen At-Home Injection Kit (NR chloride 500 mg, ~28 days)
$150–$250
Compounded Sermorelin

Niagen Plus

+Backed by a public company with 25+ years of NAD+-precursor research; it holds the patent on the active ingredient (Niagen NRCl)
+Compounded by a 503B outsourcing facility (FDA-registered, cGMP) rather than a patient-specific 503A lab alone
+Flat, published $149 kit price includes the provider consult, a ~28-day supply, supplies and free Next Day Air shipping
−Only one product, and it is NR (an NAD+ precursor), not NAD+; the studies comparing it with NAD+ IV are small and company-sponsored
−The kit showed 'more stock coming soon' at the time of research, so availability is not reliable
−The site does not name the telehealth medical group or the dispensing 503A pharmacy
Read the full Niagen Plus review →

Syra Rx

+Discloses its provider network (LocumTele) and dispensing pharmacy (Rush Pharmacy) by name in the FAQ
+One of few consumer brands offering tesamorelin alongside sermorelin and NAD+
+States a fast fulfillment window (usually 1–2 business days after approval)
−No prices published anywhere on the site; costs appear only inside third-party intake funnels
−Launched in 2026 with no independent patient reviews and no physical address disclosed
−Terms of service cover only GLP-1 services even though the site markets peptides, NAD+ and ED treatment
Read the full Syra Rx review →

Niagen Plus vs Syra Rx — FAQ

Is Niagen Plus better than Syra Rx?

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Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 53.5/100), leading on trust & safety, value, experience, reputation. Syra Rx comes out ahead on product range. Syra Rx has the lower entry price (from $30/mo vs $149/mo), so the better value depends on which treatment you need.

Is Niagen Plus or Syra Rx cheaper?

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Syra Rx has the lower starting price (from $30/mo vs $149/mo for Niagen Plus). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Niagen Plus and Syra Rx both offer?

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Both platforms treat Longevity & Peptides. Niagen Plus covers 1 treatment category total and Syra Rx covers 3.

Still deciding?

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