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Niagen Plus vs System Labs: Which Is Better?

Head-to-head comparison of Niagen Plus and System Labs based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 56.4/100), leading on trust & safety, value, experience, reputation. System Labs comes out ahead on product range. System Labs has the lower entry price (from $89/mo vs $149/mo), so the better value depends on which treatment you need.

65

Prescription-only telehealth program from Nasdaq-listed Niagen Bioscience (formerly ChromaDex) selling an at-home injection kit of nicotinamide riboside (NR), an NAD+ precursor, rather than NAD+ itself.

Visit Niagen Plus
56

System Labs is a San Francisco-based telehealth service prescribing compounded NAD+, sermorelin, glutathione and MIC-B12, with half-price first months.

Visit System Labs

Score Breakdown

DimensionNiagen PlusSystem Labs
Overall Score64.7/100 ✓56.4/100
Trust & Safety30%78/100 ✓52/100
Value25%70/100 ✓68/100
Experience20%58/100 ✓55/100
Product Range15%36/10055/100 ✓
Reputation10%68/100 ✓45/100

At a Glance

Founded2024—
HeadquartersLos Angeles, CASan Francisco, CA
Publicly tradedYes (NAGE)No
Treatment categories11
Treatments listed16
Starting price$149/mo$89/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryNiagen PlusSystem Labs
Longevity & Peptides$149
Niagen At-Home Injection Kit (NR chloride 500 mg, ~28 days)
$89
MIC+B12 Injection

Niagen Plus

+Backed by a public company with 25+ years of NAD+-precursor research; it holds the patent on the active ingredient (Niagen NRCl)
+Compounded by a 503B outsourcing facility (FDA-registered, cGMP) rather than a patient-specific 503A lab alone
+Flat, published $149 kit price includes the provider consult, a ~28-day supply, supplies and free Next Day Air shipping
−Only one product, and it is NR (an NAD+ precursor), not NAD+; the studies comparing it with NAD+ IV are small and company-sponsored
−The kit showed 'more stock coming soon' at the time of research, so availability is not reliable
−The site does not name the telehealth medical group or the dispensing 503A pharmacy
Read the full Niagen Plus review →

System Labs

+Every price is posted on the site, including a first-month discount of roughly 40–50%
+Names its main compounding pharmacy (The Pharmacy Hub, Miami) and three board-certified physician advisors
+Both injectable and non-injectable options (NAD+ nasal spray, oral sermorelin)
−Trustpilot removed its business profile for guideline violations, so there is no independent review base
−'20k+ patients' claim is unverified; founding date and company history are not disclosed
−All sales are final once shipped; terms impose binding arbitration and a class-action waiver
Read the full System Labs review →

Niagen Plus vs System Labs — FAQ

Is Niagen Plus better than System Labs?

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Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 56.4/100), leading on trust & safety, value, experience, reputation. System Labs comes out ahead on product range. System Labs has the lower entry price (from $89/mo vs $149/mo), so the better value depends on which treatment you need.

Is Niagen Plus or System Labs cheaper?

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System Labs has the lower starting price (from $89/mo vs $149/mo for Niagen Plus). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Niagen Plus and System Labs both offer?

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Both platforms treat Longevity & Peptides. Niagen Plus covers 1 treatment category total and System Labs covers 1.

Still deciding?

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