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Niagen Plus vs WellMaleRx: Which Is Better?

Head-to-head comparison of Niagen Plus and WellMaleRx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 55/100), leading on trust & safety, value, experience, reputation. WellMaleRx comes out ahead on product range. WellMaleRx has the lower entry price (from $76.99/mo vs $149/mo), so the better value depends on which treatment you need.

Niagen Plus

Fair

Prescription-only telehealth program from Nasdaq-listed Niagen Bioscience (formerly ChromaDex) selling an at-home injection kit of nicotinamide riboside (NR), an NAD+ precursor, rather than NAD+ itself.

Visit Niagen Plus

WellMaleRx

Fair

WellMaleRx is a new compounded-medication telehealth storefront offering seven multi-ingredient ED formulas (including 'Overdrive Plus') and nine NAD+, glutathione and MIC/B12 longevity products.

Visit WellMaleRx

Score Breakdown

Dimension	Niagen Plus	WellMaleRx
Overall Score	64.7/100 ✓	55/100
Trust & Safety30%	78/100 ✓	50/100
Value25%	70/100 ✓	64/100
Experience20%	58/100 ✓	55/100
Product Range15%	36/100	60/100 ✓
Reputation10%	68/100 ✓	40/100

At a Glance

Founded	2024	2026
Headquarters	Los Angeles, CA	—
Publicly traded	Yes (NAGE)	No
Treatment categories	1	3
Treatments listed	1	7
Starting price	$149/mo	$76.99/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

Category	Niagen Plus	WellMaleRx
Longevity & Peptides	$149 Niagen At-Home Injection Kit (NR chloride 500 mg, ~28 days)	$79.5–$159 Lipolean (MIC/B12)

Niagen Plus

+Backed by a public company with 25+ years of NAD+-precursor research; it holds the patent on the active ingredient (Niagen NRCl)

+Compounded by a 503B outsourcing facility (FDA-registered, cGMP) rather than a patient-specific 503A lab alone

+Flat, published $149 kit price includes the provider consult, a ~28-day supply, supplies and free Next Day Air shipping

−Only one product, and it is NR (an NAD+ precursor), not NAD+; the studies comparing it with NAD+ IV are small and company-sponsored

−The kit showed 'more stock coming soon' at the time of research, so availability is not reliable

−The site does not name the telehealth medical group or the dispensing 503A pharmacy

Read the full Niagen Plus review →

WellMaleRx

+Per-pack and per-dose pricing is published for every formula before intake

+Wide compounded ED range (seven formulas incl. bremelanotide and apomorphine combinations) plus NAD+ and glutathione in injectable, nasal and patch forms

+States one-click pause, skip or cancel from the patient dashboard with no cancellation fee

−No operating company, founders, medical group or pharmacy is named anywhere on the site

−$40 consultation fee is charged when an intake is declined or incomplete

−Advertised first-order prices are intro rates; refills bill at a higher 'member rate' (e.g. NAD+ $99.50 first month, then $199/month)

Read the full WellMaleRx review →

Niagen Plus vs WellMaleRx — FAQ

Is Niagen Plus better than WellMaleRx?

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Is Niagen Plus or WellMaleRx cheaper?

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WellMaleRx has the lower starting price (from $76.99/mo vs $149/mo for Niagen Plus). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Niagen Plus and WellMaleRx both offer?

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Both platforms treat Longevity & Peptides. Niagen Plus covers 1 treatment category total and WellMaleRx covers 3.

Still deciding?

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