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Niagen Plus vs Wellmedr: Which Is Better?

Head-to-head comparison of Niagen Plus and Wellmedr based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 60.8/100), leading on trust & safety, experience, reputation. Wellmedr comes out ahead on value, product range. Wellmedr has the lower entry price (from $40/mo vs $149/mo), so the better value depends on which treatment you need.

Niagen Plus

Fair

Prescription-only telehealth program from Nasdaq-listed Niagen Bioscience (formerly ChromaDex) selling an at-home injection kit of nicotinamide riboside (NR), an NAD+ precursor, rather than NAD+ itself.

Visit Niagen Plus

Wellmedr

Fair

Wellmedr is a St. Petersburg, FL telehealth brand launched in 2025. It sells low-priced compounded semaglutide and tirzepatide plus ED, enclomiphene, hair-loss and NAD+ treatments, prescribed through OpenLoop Health.

Visit Wellmedr

Score Breakdown

Dimension	Niagen Plus	Wellmedr
Overall Score	64.7/100 ✓	60.8/100
Trust & Safety30%	78/100 ✓	50/100
Value25%	70/100	78/100 ✓
Experience20%	58/100 ✓	55/100
Product Range15%	36/100	72/100 ✓
Reputation10%	68/100 ✓	45/100

At a Glance

Founded	2024	2025
Headquarters	Los Angeles, CA	St. Petersburg, FL
Publicly traded	Yes (NAGE)	No
Treatment categories	1	6
Treatments listed	1	6
Starting price	$149/mo	$40/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

Category	Niagen Plus	Wellmedr
Longevity & Peptides	$149 Niagen At-Home Injection Kit (NR chloride 500 mg, ~28 days)	$120–$200 NAD+

Niagen Plus

+Backed by a public company with 25+ years of NAD+-precursor research; it holds the patent on the active ingredient (Niagen NRCl)

+Compounded by a 503B outsourcing facility (FDA-registered, cGMP) rather than a patient-specific 503A lab alone

+Flat, published $149 kit price includes the provider consult, a ~28-day supply, supplies and free Next Day Air shipping

−Only one product, and it is NR (an NAD+ precursor), not NAD+; the studies comparing it with NAD+ IV are small and company-sponsored

−The kit showed 'more stock coming soon' at the time of research, so availability is not reliable

−The site does not name the telehealth medical group or the dispensing 503A pharmacy

Read the full Niagen Plus review →

Wellmedr

+Some of the lowest compounded GLP-1 prices we track: $49/mo semaglutide and $89/mo tirzepatide on 12-month plans, the same at every dose

+Broad catalog for a new brand, spanning GLP-1s, a 3-in-1 ED pill, enclomiphene, a 4-in-1 hair-loss formula and NAD+

+Unlimited clinician messaging and 1–4 hour approval target; 90-day money-back guarantee advertised

−BBB rating of F with 75 complaints since its May 2025 start; BBB flagged a pattern of late or temperature-mishandled deliveries, charges after cancellation and refused guarantee refunds

−Reviewers report billing every 21 days rather than monthly, which adds charges over a year

−Dispensing pharmacies are not named, and prescribing is outsourced to OpenLoop Health and 'other networks'

Read the full Wellmedr review →

Niagen Plus vs Wellmedr — FAQ

Is Niagen Plus better than Wellmedr?

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Is Niagen Plus or Wellmedr cheaper?

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Wellmedr has the lower starting price (from $40/mo vs $149/mo for Niagen Plus). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Niagen Plus and Wellmedr both offer?

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Both platforms treat Longevity & Peptides. Niagen Plus covers 1 treatment category total and Wellmedr covers 6.

Still deciding?

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